Issue 10, 2019

Facile reduction of carboxylic acids to primary alcohols under catalyst-free and solvent-free conditions

Abstract

We report the development of a facile protocol for the deoxygenative hydroboration of aliphatic and aryl carboxylic acids to afford corresponding primary alcohols under solvent-free and catalyst-free conditions. The reaction proceeds under ambient temperature exhibits good tolerance towards various functional groups and generates quantitative yields. The plausible mechanism involves the formation of Lewis acid–base adducts as well as the liberation of hydrogen gas.

Graphical abstract: Facile reduction of carboxylic acids to primary alcohols under catalyst-free and solvent-free conditions

Supplementary files

Article information

Article type
Communication
Submitted
06 Huk 2018
Accepted
21 N’w 2018
First published
21 N’w 2018

Chem. Commun., 2019,55, 1386-1389

Facile reduction of carboxylic acids to primary alcohols under catalyst-free and solvent-free conditions

A. Harinath, J. Bhattacharjee and T. K. Panda, Chem. Commun., 2019, 55, 1386 DOI: 10.1039/C8CC08841A

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