Issue 6, 2013

Enantioselective cooperative triple catalysis: unique roles of Au(i)/amine/chiral Brønsted acid catalysts in the addition/cycloisomerization/transfer hydrogenation cascade

Abstract

An enantioselective cooperative process involving the concerted/simultaneous action of three different catalysts i.e. Au(I)/amine/chiral Brønsted acid catalysts has been realized for the synthesis of 2-substituted tetrahydroquinolines from 2-aminobenzaldehydes and terminal alkynes.

Graphical abstract: Enantioselective cooperative triple catalysis: unique roles of Au(i)/amine/chiral Brønsted acid catalysts in the addition/cycloisomerization/transfer hydrogenation cascade

Supplementary files

Article information

Article type
Communication
Submitted
19 Nhl 2012
Accepted
14 Huk 2012
First published
15 Huk 2012

Chem. Commun., 2013,49, 570-572

Enantioselective cooperative triple catalysis: unique roles of Au(I)/amine/chiral Brønsted acid catalysts in the addition/cycloisomerization/transfer hydrogenation cascade

N. T. Patil, V. S. Raut and R. B. Tella, Chem. Commun., 2013, 49, 570 DOI: 10.1039/C2CC37623G

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