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We use a range of spectroscopic methods to provide mechanistic insight into a phosphatase-driven supramolecular transformation whereby an amphiphilic peptide building block, upon dephosphorylation, switches from a solution-phase, micellar structure to a gel-phase, chiral uni-directional nanofibre morphology.

Graphical abstract: Micelle to fibre biocatalytic supramolecular transformation of an aromatic peptide amphiphile

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