Issue 42, 2023

Recent advances on the construction of long-wavelength emissive supramolecular coordination complexes for photo-diagnosis and therapy

Abstract

Recently, metal-based drugs have attracted relentless interest in the biomedical field. However, their short excitation/emission wavelengths and unsatisfactory therapeutic efficiency limit their biological applications in vivo. Currently, the second near-infrared window (NIR-II, 1000–1700 nm) provides more accurate imaging and therapeutic options. Thus, there has been a constant focus on developing multifunctional NIR metal agents for imaging and therapy that have deeper tissue penetration. Fortunately, supramolecular coordination complexes (SCCs) formed by the coordination-driven self-assembly of NIR-II emissive ligands can address the above issues. Importantly, metal receptors with chemotherapeutic properties in SCCs can bind to luminescent ligands, thus becoming a versatile therapeutic platform for chemotherapy, imaging and phototherapy. In this context, we systematically summarize the evolution of NIR-II emissive SCCs for biomedical applications and discuss future challenges and prospects.

Graphical abstract: Recent advances on the construction of long-wavelength emissive supramolecular coordination complexes for photo-diagnosis and therapy

Article information

Article type
Perspective
Submitted
18 Kho 2023
Accepted
17 Maw 2023
First published
18 Maw 2023

Dalton Trans., 2023,52, 15193-15202

Recent advances on the construction of long-wavelength emissive supramolecular coordination complexes for photo-diagnosis and therapy

Z. Zhang, H. Ye, F. Cai and Y. Sun, Dalton Trans., 2023, 52, 15193 DOI: 10.1039/D3DT01893H

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