Issue 41, 2019

Plasmonic bimetallic nanodisk arrays for DNA conformation sensing

Abstract

The integration of large-scale 2D bimetallic Ag/Au nanodisk arrays with gold nanoparticles is developed for sensing DNA conformation with the assistance of 3D finite-difference time-domain simulation. The optimized system comprising Ag/Au nanodisk arrays and gold nanoparticles offers a more than 6-fold enhancement in surface plasmon resonance shift, enabling the feasibility for sensitive DNA detection with a detection limit down to 100 femtomolar. Importantly, owing to the distance-dependent nature of the surface plasmon signal, sensitive differentiation of DNA conformations can be achieved with a conventional optical measurement. This platform could provide new exciting capabilities for a reliable, reproducible, and label-free assay analysis for investigating the conformations of DNA and other biological molecules.

Graphical abstract: Plasmonic bimetallic nanodisk arrays for DNA conformation sensing

Supplementary files

Article information

Article type
Communication
Submitted
18 Maw 2019
Accepted
08 Ndz 2019
First published
09 Ndz 2019

Nanoscale, 2019,11, 19291-19296

Plasmonic bimetallic nanodisk arrays for DNA conformation sensing

T. T. V. Nguyen, X. Xie, J. Xu, Y. Wu, M. Hong and X. Liu, Nanoscale, 2019, 11, 19291 DOI: 10.1039/C9NR06101K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements