Issue 27, 2019

Calibration strategies to correct for matrix effects in direct analysis of urine by ICP OES: internal standardization and multi-energy calibration

Abstract

This study investigated internal standardization and multi-energy calibration (MEC) as strategies for direct analysis of urine by inductively coupled plasma optical emission spectrometry (ICP OES). Gallium, Ge, Pd, Sc and Y were evaluated as internal standards (ISs) for determination of Al, As, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Hg, K, Li, Mg, Na, Pb, Sb and Zn in urine. The accuracy and precision were evaluated by addition–recovery experiments and the best results were obtained when Ge or Pd was used as IS. Recoveries ranged from 80 to 120% and relative standard deviations for all elements and samples were lower than 7.5%, except in the case of the lowest analyte levels (0.025 and 0.050 mg L−1). Recoveries varying from 80 to 120% were obtained only for the highest levels tested (>4.0 mg L−1) when using MEC. The LODs obtained by internal standardization were lower than the LODs obtained by MEC. Both calibration methods were suitable to correct for matrix effects, making feasible the direct analysis of urine by ICP OES, without any sample preparation.

Graphical abstract: Calibration strategies to correct for matrix effects in direct analysis of urine by ICP OES: internal standardization and multi-energy calibration

Supplementary files

Article information

Article type
Paper
Submitted
29 Dzi 2019
Accepted
13 Kho 2019
First published
17 Kho 2019

Anal. Methods, 2019,11, 3401-3409

Calibration strategies to correct for matrix effects in direct analysis of urine by ICP OES: internal standardization and multi-energy calibration

A. I. Barros, F. C. Pinheiro and J. A. Nóbrega, Anal. Methods, 2019, 11, 3401 DOI: 10.1039/C9AY00907H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements