A new route for synthesizing diisocyanates containing a furan ring structure from renewable biomass is proposed. The yield of each step is high, and the reaction conditions are mild and easy to operate, offering prospects for industrialization.
A new green route was developed from renewable resource 5-HMF to bio-based isocyanate HDI to avoid using highly toxic phosgene.
In this review, we provide an overview of alkaloid syntheses reported since 2017, categorized by scaffold, with a focus on key steps involving asymmetric reactions catalyzed by secondary amine organocatalysts.
The tetrahydrofuran diesters were successfully synthesized, demonstrating wide applicability as replacements for conventional base oils. They also showed a 35% reduction in CO2 emissions, as revealed by LCA analysis.
The review focuses on gold-catalyzed nucleophilic and electrophilic fluorination of alkynes and allenes to direct access the valuable fluoroalkanes, fluoroalkenes, α-fluorocarbonyls, and fluorinated carbo- and hetero-cycles.