This review highlights recent advances in fluorescent isoquinolinium salts, focusing on their applications in bioimaging, DNA binding, theranostics, and sensing.
Catalytic isoquinoline-based EDA complex photoreduced alkylative [3 + 2] annulation of alkynes with N-alkyl isoquinolin-2-iums toward pyrrolo[2,1-a]isoquinolines is depicted.
The strategic union of distinct azolium salts through double dearomatization, driven by inverse electron-demand (4 + 2) and (3 + 2) annulations, enables the regio- and diastereoselective synthesis of intricate caged tertiary amines in high yields.
Herein we reported the direct use of hydroxyl ions as an oxygen source for oxidation of isoquinolinium salts to isoquinolinones in water solution.
A mild and transition-metal-free strategy for alternative synthesis of isoindolin-1-imines and isoquinolinium salts has been developed using ortho-ethynylbenzaldehydes and anilines.