Palladium-catalyzed oxidative amination of homoallylic alcohols: sequentially installing carbonyl and amino groups along an alkyl chain

Lu Ouyang, Jiuzhong Huang, Jianxiao Li, Chaorong Qi, Wanqing Wu and Huanfeng Jiang

Chem. Commun., 2017, 53, 10422
DOI: 10.1039/C7CC06077G

Transition metal-catalyzed sp3 C–H activation and intramolecular C–N coupling to construct nitrogen heterocyclic scaffolds

Ming Zhang, Qiuhong Wang, Yiyuan Peng, Zhiyuan Chen, Changfeng Wan, Junmin Chen, Yongli Zhao, Rongli Zhang and Ai Qin Zhang

Chem. Commun., 2019, 55, 13048
DOI: 10.1039/C9CC06609H

Cobalt-catalysed unactivated C(sp3)–H amination: two-state reactivity and multi-reference electronic character

Yang Yu, Gen Luo, Jimin Yang and Yi Luo

Catal. Sci. Technol., 2019, 9, 1879
DOI: 10.1039/C9CY00239A

Synthesis of lactones and lactams via C(sp3)–H bond functionalization

Egambaram Premkumar, Ramdas Sreedharan, Premananda Ghosh, Tanay Pal, Debabrata Maiti and Thirumanavelan Gandhi

Chem. Soc. Rev., 2025, 54, 6238
DOI: 10.1039/D4CS01152J

Site-selective and diastereoselective functionalization of α-amino acid and peptide derivatives via palladium-catalyzed sp3 C–H activation

Ming Zhang, Shengliang Zhong, Yiyuan Peng, Jianwen Jiang, Yongli Zhao, Changfeng Wan, Zhenming Zhang, Rongli Zhang and Ai Qin Zhang

Org. Chem. Front., 2021, 8, 133
DOI: 10.1039/D0QO00988A

Recent advances in β-lactam synthesis

Seyedmorteza Hosseyni and Aliasghar Jarrahpour

Org. Biomol. Chem., 2018, 16, 6840
DOI: 10.1039/C8OB01833B

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

Carlo Sambiagio, David Schönbauer, Remi Blieck, Toan Dao-Huy, Gerit Pototschnig, Patricia Schaaf, Thomas Wiesinger, Muhammad Farooq Zia, Joanna Wencel-Delord, Tatiana Besset, Bert U. W. Maes and Michael Schnürch

Chem. Soc. Rev., 2018, 47, 6603
DOI: 10.1039/C8CS00201K

Metal-free regioselective C–H amination for the synthesis of pyrazole-containing 2H-indazoles

Kai Wang, Tingting Wei, Yujia Zhang, Jiahao Hou, Renren Bai and Yuanyuan Xie

Org. Biomol. Chem., 2021, 19, 1787
DOI: 10.1039/D0OB02485F

A practical copper-catalyzed approach to β-lactams via radical carboamination of alkenyl carbonyl compounds

Peng Shi, Jie Wang, Zixu Gan, Jingyu Zhang, Runsheng Zeng and Yingsheng Zhao

Chem. Commun., 2019, 55, 10523
DOI: 10.1039/C9CC05668H

Copper(i)-catalyzed radical carboamination reaction of 8-aminoquinoline-oriented buteneamides with chloroform: synthesis of-β-lactams

Zixu Gan, Ke Zhang, Peng Shi, Yingsheng Zhao and Runsheng Zeng

RSC Adv., 2021, 11, 28081
DOI: 10.1039/D1RA05233K

Palladium-catalyzed intramolecular C–H amination using aluminum nitrate as the oxidant

Kai Jia, Yuan Xue, Daoquan Tu, Jun Luo and Chao Jiang

Org. Chem. Front., 2023, 10, 109
DOI: 10.1039/D2QO01562E

Removal and modification of directing groups used in metal-catalyzed C–H functionalization: the magical step of conversion into ‘conventional’ functional groups

Renato L. Carvalho, Renata G. Almeida, Karunanidhi Murali, Luana A. Machado, Leandro F. Pedrosa, Pravas Dolui, Debabrata Maiti and Eufrânio N. da Silva Júnior

Org. Biomol. Chem., 2021, 19, 525
DOI: 10.1039/D0OB02232B

Synthesis of Spirofluorenyl‐β‐Lactams through Cycloaddition and Ring Contraction from N‐Aryl Fluorenone Nitrones and Methylenecyclopropanes

Cui Wei, Jie‐Feng Zhu, Jin‐Qi Zhang, Qi Deng and Dong‐Liang Mo

Adv Synth Catal, 2019, 361, 3965
DOI: 10.1002/adsc.201900523

Visible-Light-Mediated Nickel(II)-Catalyzed C–N Cross-Coupling in Water: Green and Regioselective Access for the Synthesis of Pyrazole-Containing Compounds

Guirong You, Kai Wang, Xiaodan Wang, Guodong Wang, Jian Sun, Guiyun Duan and Chengcai Xia

Org. Lett., 2018, 20, 4005
DOI: 10.1021/acs.orglett.8b01395

Oxone-Mediated Radical C–C Bond Acetmethylation/Arylation of Methylenecyclopropanes and Vinylcyclopropanes with α-Alkyl Ketones: Facile Access to Oxoalkyl-Substituted 3,4-Dihydronaphthalenes

Yu Liu, Qiao-Lin Wang, Zan Chen, Quan Zhou, Hua Li, Wen-Yuan Xu, Bi-Quan Xiong and Ke-Wen Tang

J. Org. Chem., 2019, 84, 5413
DOI: 10.1021/acs.joc.9b00407

Experimental and Computational Studies on Remote γ-C(sp3)–H Silylation and Germanylation of Aliphatic Carboxamides

Arghya Deb, Sukriti Singh, Kapileswar Seth, Sandeep Pimparkar, Bangaru Bhaskararao, Srimanta Guin, Raghavan B. Sunoj and Debabrata Maiti

ACS Catal., 2017, 7, 8171
DOI: 10.1021/acscatal.7b03056

Palladium‐Catalyzed 8‐Aminoquinoline‐Aided sp2δ‐C−H Intramolecular Amidation/Annulation: A Route to Tricyclic Quinolones

Rayavarapu Padmavathi and Srinivasarao Arulananda Babu

Asian J Org Chem, 2019, 8, 899
DOI: 10.1002/ajoc.201900109

Catalytic Direct α-Amination of Arylacetic Acid Synthons with Anilines

Jogendra Kumar, Eringathodi Suresh and Sukalyan Bhadra

J. Org. Chem., 2020, 85, 13363
DOI: 10.1021/acs.joc.0c02122

Ligand‐Enabled β‐C(sp3)−H Lactamization of Tosyl‐Protected Aliphatic Amides Using a Practical Oxidant

Zhe Zhuang, Shuang Liu, Jin‐Tang Cheng, Kap‐Sun Yeung, Jennifer X. Qiao, Nicholas A. Meanwell and Jin‐Quan Yu

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202207354

A Guide to Directing Group Removal: 8‐Aminoquinoline

Liam S. Fitzgerald and Miriam L. O'Duill

Chemistry A European J, 2021, 27, 8411
DOI: 10.1002/chem.202100093

Bidentate Directing Groups: An Efficient Tool in C–H Bond Functionalization Chemistry for the Expedient Construction of C–C Bonds

Supriya Rej, Yusuke Ano and Naoto Chatani

Chem. Rev., 2020, 120, 1788
DOI: 10.1021/acs.chemrev.9b00495

A Simple Aliphatic Diamine Auxiliary for Palladium‐Catalyzed Arylation of Unactivated β‐C(sp3)‐H Bonds

Jiang Lou, Quannan Wang, Yuan He and Zhengkun Yu

Adv Synth Catal, 2018, 360, 4571
DOI: 10.1002/adsc.201801022

Organocatalytic Cloke–Wilson Rearrangement: Carbocation-Initiated Tandem Ring Opening/Cyclization of Cyclopropanes under Neutral Conditions

Guisheng Zhang, Liming Chen, Zhaokang Hu, Zhiguo Zhang, Jingjing Bi, Mengjuan Li and Xingjie Zhang

J. Org. Chem., 2023, 88, 1003
DOI: 10.1021/acs.joc.2c02415

Synthesis of Chiral β‐Lactams by Pd‐Catalyzed Enantioselective Amidation of Methylene C(sp3)–H Bonds

Tao Zhou, Meng‐Xue Jiang, Xu Yang, Qiang Yue, Ye‐Qiang Han, Yi Ding and Bing‐Feng Shi

Chin. J. Chem., 2020, 38, 242
DOI: 10.1002/cjoc.201900533

C–H activation: A strategic approach toward lactams using transition metals

Subhabrata Dutta, Sagnik Chatterjee, Shaeel A. Al-Thabaiti, Salem Bawaked, Mohamed Mokhtar and Debabrata Maiti

Chem Catalysis, 2022, 2, 1046
DOI: 10.1016/j.checat.2022.03.027

Utility of 4‐Amino‐2,1,3‐benzothiadiazole Directing Group in the Pd(II)‐catalyzed Arylation of γ‐C−H Bonds of Carboxamides and β‐C‐H Bonds of Amino Acid Carboxamides

Narendra Bisht, Srinivasarao Arulananda Babu and Radha Tomar

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202200589

Construction of Racemic and Enantiopure Biaryl Unnatural Amino Acid Derivatives via Pd(II)‐Catalyzed Arylation of Unactivated Csp3−H Bonds

Shefali Banga, Ramandeep Kaur and Srinivasarao Arulananda Babu

Eur J Org Chem, 2021, 2021, 3641
DOI: 10.1002/ejoc.202100683

Copper-catalyzed benzylic C–H amidation of toluene derivatives with N-(8-quinolyl)amides through C(sp3)–H/N–H cross dehydrogenative coupling

Huihui Ji, Zhigang Wang, Hongju Zhan, Zeguo Fang, Qian Zhang and Dong Li

Tetrahedron, 2022, 127, 133066
DOI: 10.1016/j.tet.2022.133066

Selective O-Cyclization of N-Methoxy Aryl Amides with CH2Br2 or 1,2-DCE via Palladium-Catalyzed C–H Activation

Wei-Hao Rao, Li-Li Jiang, Jin-Xiao Zhao, Xin Jiang, Guo-Dong Zou, Yu-Qiang Zhou and Lin Tang

Org. Lett., 2018, 20, 6198
DOI: 10.1021/acs.orglett.8b02678

Ligand‐Enabled β‐C(sp3)−H Lactamization of Tosyl‐Protected Aliphatic Amides Using a Practical Oxidant

Zhe Zhuang, Shuang Liu, Jin‐Tang Cheng, Kap‐Sun Yeung, Jennifer X. Qiao, Nicholas A. Meanwell and Jin‐Quan Yu

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202207354

Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)–H Bonds

Bin Liu, Andrew M. Romine, Camille Z. Rubel, Keary M. Engle and Bing-Feng Shi

Chem. Rev., 2021, 121, 14957
DOI: 10.1021/acs.chemrev.1c00519

Synthesis of polycyclic spiro-fused indolines via IBX-mediated cascade cyclization

Zhiguo Zhang, Xiaoqing Song, Guofeng Li, Xiang Li, Dan Zheng, Xuna Zhao, Huanran Miao, Guisheng Zhang and Lantao Liu

Chinese Chemical Letters, 2021, 32, 1423
DOI: 10.1016/j.cclet.2020.11.001

C(sp3)–H Monoarylation of Methanol Enabled by a Bidentate Auxiliary

Quan Gou, Binfang Yuan, Man Ran, Jian Ren, Ming-zhong Zhang, Xiaoping Tan, Tengrui Yuan and Xing Zhang

Org. Lett., 2021, 23, 118
DOI: 10.1021/acs.orglett.0c03786

Transition‐Metal‐Catalyzed Annulations Involving the Activation of C(sp3)−H Bonds

Marc Font, Moisés Gulías and José Luis Mascareñas

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202112848

Transition‐Metal‐Catalyzed Annulations Involving the Activation of C(sp3)−H Bonds

Marc Font, Moisés Gulías and José Luis Mascareñas

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202112848

Pd‐Catalyzed Trifluoromethylthiolation of Unsaturated Compounds: A General Approach

Qun Zhao, Mu‐Yi Chen, Thomas Poisson, Xavier Pannecoucke, Jean‐Philippe Bouillon and Tatiana Besset

Eur J Org Chem, 2018, 2018, 6167
DOI: 10.1002/ejoc.201801071

Synthesis of α-Methylene-β-lactams Enabled by Base-Promoted Intramolecular 1,2-Addition of N-Propiolamide and C–C Bond Migrating Cleavage of Aziridine

Lianpeng Zhang, Lele Ma, Hongwei Zhou, Jinzhong Yao, Xiaofang Li and Guanyinsheng Qiu

Org. Lett., 2018, 20, 2407
DOI: 10.1021/acs.orglett.8b00742