Amphiphilic dendrimers against antibiotic resistance: light at the end of the tunnel?

Christina Galanakou, Dinesh Dhumal and Ling Peng

Biomater. Sci., 2023, 11, 3379
DOI: 10.1039/D2BM01878K

Aza-Michael promoted glycoconjugation of PETIM dendrimers and selectivity in mycobacterial growth inhibitions

Biswajit Sarkar, Avisek Mahapa, Kalyan Dey, Rakshit Manhas, Dipankar Chatterji and Narayanaswamy Jayaraman

RSC Adv., 2023, 13, 4669
DOI: 10.1039/D2RA08196B

Amphiphilic cationic copolymers with ciprofloxacin: preparation and antimicrobial activities

Man He, Yuming Zhou, Huining Xiao and Peng Lu

New J. Chem., 2016, 40, 1354
DOI: 10.1039/C5NJ02145F

Bio-inspired peptide decorated dendrimers for a robust antibacterial coating on hydroxyapatite

Yaping Gou, Xiao Yang, Libang He, Xinyuan Xu, Yanpeng Liu, Yuebo Liu, Yuan Gao, Qin Huang, Kunneng Liang, Chunmei Ding, Jiyao Li, Changsheng Zhao and Jianshu Li

Polym. Chem., 2017, 8, 4264
DOI: 10.1039/C7PY00811B

Chemically modified and conjugated antimicrobial peptides against superbugs

Wenyi Li, Frances Separovic, Neil M. O'Brien-Simpson and John D. Wade

Chem. Soc. Rev., 2021, 50, 4932
DOI: 10.1039/D0CS01026J

Dynamic self-assembling supramolecular dendrimer nanosystems as potent antibacterial candidates against drug-resistant bacteria and biofilms

Dinesh Dhumal, Bar Maron, Einav Malach, Zhenbin Lyu, Ling Ding, Domenico Marson, Erik Laurini, Aura Tintaru, Brigino Ralahy, Suzanne Giorgio, Sabrina Pricl, Zvi Hayouka and Ling Peng

Nanoscale, 2022, 14, 9286
DOI: 10.1039/D2NR02305A

Structure‐Activity Relationships for Poly(phenylene)vinylene Derivatives as Antibacterial Agents

Juan Tolosa, Gemma Serrano de las Heras, Blanca Carrión, Tomás Segura, Paulina L. Páez, Fernando J. de Lera‐Garrido, Julián Rodríguez‐López and Joaquín C. García‐Martínez

ChemistrySelect, 2018, 3, 7327
DOI: 10.1002/slct.201801287

Antimicrobial Organometallic Dendrimers with Tunable Activity against Multidrug-Resistant Bacteria

Alaa S. Abd-El-Aziz, Christian Agatemor, Nola Etkin, David P. Overy, Martin Lanteigne, Katherine McQuillan and Russell G. Kerr

Biomacromolecules, 2015, 16, 3694
DOI: 10.1021/acs.biomac.5b01207

Synthesis, characterisaion and antimicrobial activity of polypropylenamine metallodendrimers modified with 1,8-naphthalimides

Desislava Staneva, Ivo Grabchev, Paula Bosch, Evgenia Vasileva-Tonkova, Rositsa Kukeva and Radostina Stoyanova

Journal of Molecular Structure, 2018, 1164, 363
DOI: 10.1016/j.molstruc.2018.03.017

Nanoengineered Drug Delivery Systems for Enhancing Antibiotic Therapy

Rahul S. Kalhapure, Nadia Suleman, Chunderika Mocktar, Nasreen Seedat and Thirumala Govender

Journal of Pharmaceutical Sciences, 2015, 104, 872
DOI: 10.1002/jps.24298

Brief Timelapse on Dendrimer Chemistry: Advances, Limitations, and Expectations

Catia Ornelas

Macro Chemistry & Physics, 2016, 217, 149
DOI: 10.1002/macp.201500393

From Nanobiotechnology, Positively Charged Biomimetic Dendrimers as Novel Antibacterial Agents: A Review

Silvana Alfei and Anna Maria Schito

Nanomaterials, 2020, 10, 2022
DOI: 10.3390/nano10102022

In vitro antibacterial activity of poly (amidoamine)-G7 dendrimer

Mitra Gholami, Rashin Mohammadi, Mohsen Arzanlou, Fakhraddin Akbari Dourbash, Ebrahim Kouhsari, Gharib Majidi, Seyed Mohsen Mohseni and Shahram Nazari

BMC Infect Dis, 2017, 17
DOI: 10.1186/s12879-017-2513-7

Exploiting Dendrimer Multivalency To Combat Emerging and Re-Emerging Infectious Diseases

Meredith A. Mintzer, Eric L. Dane, George A. O’Toole and Mark W. Grinstaff

Mol. Pharmaceutics, 2012, 9, 342
DOI: 10.1021/mp2005033

Continuous Flow Atomic Force Microscopy Imaging Reveals Fluidity and Time-Dependent Interactions of Antimicrobial Dendrimer with Model Lipid Membranes

Tania Kjellerup Lind, Paulina Zielińska, Hanna Pauliina Wacklin, Zofia Urbańczyk-Lipkowska and Marité Cárdenas

ACS Nano, 2014, 8, 396
DOI: 10.1021/nn404530z

Light-driven self-sterilizing cotton fabric and drug delivery: improvement of the antimicrobial activity of 4-sulfo-1,8-naphthalimide via its dendrimer and metallic dendrimer formation

Desislava Staneva, Awad I. Said, Petar Grozdanov, Ivanka Nikolova, Radostina Stoyanova, Albena Jordanova and Ivo Grabchev

Photochem Photobiol Sci, 2025, 24, 593
DOI: 10.1007/s43630-025-00710-1

Targeting the phosphatidylglycerol lipid: An amphiphilic dendrimer as a promising antibacterial candidate

Nian Zhang, Dinesh Dhumal, Shanny Hsuan Kuo, Shi Qian Lew, Pankaj D. Patil, Raleb Taher, Sanika Vaidya, Christina Galanakou, Abdechakour Elkihel, Myung Whan Oh, Sook Yin Chong, Domenico Marson, Jun Zheng, Oleg Rouvinski, Williams O. Abolarin, Sabrina Pricl, Gee W. Lau, Leo Tsz On Lee and Ling Peng

Sci. Adv., 2024, 10
DOI: 10.1126/sciadv.adn8117

Dendrimer space concept for innovative nanomedicine: A futuristic vision for medicinal chemistry

Serge Mignani, Saïd El Kazzouli, Mosto Bousmina and Jean-Pierre Majoral

Progress in Polymer Science, 2013, 38, 993
DOI: 10.1016/j.progpolymsci.2013.03.003

Emerging concepts in dendrimer‐based nanomedicine: from design principles to clinical applications

R. M. Kannan, E. Nance, S. Kannan and D. A. Tomalia

J Intern Med, 2014, 276, 579
DOI: 10.1111/joim.12280

Applications of Dendrimers in Nanomedicine and Drug Delivery: A Review

Mohammad Nikzamir, Younes Hanifehpour, Abolfazl Akbarzadeh and Yunes Panahi

J Inorg Organomet Polym, 2021, 31, 2246
DOI: 10.1007/s10904-021-01925-2

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Guillermo Landa, Gracia Mendoza, Silvia Irusta and Manuel Arruebo

Advanced Materials, 2025
DOI: 10.1002/adma.202510355

Amino-Terminated Generation 2 Poly(amidoamine) Dendrimer as a Potential Broad-Spectrum, Nonresistance-Inducing Antibacterial Agent

Xiaoyan Xue, Xiaoqing Chen, Xinggang Mao, Zheng Hou, Ying Zhou, Hui Bai, Jingru Meng, Fei Da, Guojun Sang, Yukun Wang and Xiaoxing Luo

AAPS J, 2013, 15, 132
DOI: 10.1208/s12248-012-9416-8

Carbosilane dendrimers: Drug and gene delivery applications

Navid Rabiee, Shokooh Ahmadvand, Sepideh Ahmadi, Yousef Fatahi, Rassoul Dinarvand, Mojtaba Bagherzadeh, Mohammad Rabiee, Mohammadreza Tahriri, Lobat Tayebi and Michael R. Hamblin

Journal of Drug Delivery Science and Technology, 2020, 59, 101879
DOI: 10.1016/j.jddst.2020.101879

Unveiling Hierarchical Self‐Assembly of Triazolylferrocenyl Dendrimers: Producing Non‐Traditional Intrinsically Green Fluorescent Vesosomes for Nanotheranostics

Carolyne B. Braga, Gabriel Perli, Qi Wang, Luke Wylie, Diego L. Bertuzzi, Marco C. P. Soares, Miguel D. Ramos, Jaime Ruiz, Agilio Padua, Didier Astruc and Catia Ornelas

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202402888

Enhancing the antibacterial activity of PAMAM dendrimer modified with 1,8‐naphthalimides and its copper complex via light illumination

Desislava Staneva, Hristo Manov, Evgenia Vasileva‐Tonkova, Rositsa Kukeva, Radostina Stoyanova and Ivo Grabchev

Polymers for Advanced Techs, 2022, 33, 3163
DOI: 10.1002/pat.5768

Synthesis, photophysical characterisation and antimicrobial activity of a new anionic PAMAM dendrimer

Desislava Staneva, Silvia Angelova, Evgenia Vasileva-Tonkova, Peter Grozdanov, Ivanka Nikolova and Ivo Grabchev

Journal of Photochemistry and Photobiology A: Chemistry, 2020, 403, 112878
DOI: 10.1016/j.jphotochem.2020.112878

Novel Antimicrobial Peptide Dendrimers with Amphiphilic Surface and Their Interactions with Phospholipids — Insights from Mass Spectrometry

Piotr Polcyn, Paulina Zielinska, Magdalena Zimnicka, Anna Troć, Przemysław Kalicki, Jolanta Solecka, Anna Laskowska and Zofia Urbanczyk-Lipkowska

Molecules, 2013, 18, 7120
DOI: 10.3390/molecules18067120

Synthesis and Characterization of a New PAMAM Metallodendrimer for Antimicrobial Modification of Cotton Fabric

Desislava Staneva, Evgenia Vasileva-Tonkova, Paula Bosch, Peter Grozdanov and Ivo Grabchev

Macromol. Res., 2018, 26, 332
DOI: 10.1007/s13233-018-6043-x

Spectral characterization, antimicrobial and antibiofilm activity of poly(propylene imine) metallodendrimers in solution and applied onto cotton fabric

Desislava Staneva, Evgenia Vasileva-Tonkova, Stanislava Yordanova, Rositsa Kukeva, Radostina Stoyanova and Ivo Grabchev

International Journal of Polymer Analysis and Characterization, 2020, 25, 374
DOI: 10.1080/1023666X.2020.1796105

ChemInform Abstract: Dendrimers as Bactericides

Annie Castonguay, Elizabeth Ladd, Theo G. M. van de Ven and Ashok Kakkar

ChemInform, 2012, 43
DOI: 10.1002/chin.201221263

Design and Synthesis of Dendrimers with Facile Surface Group Functionalization, and an Evaluation of Their Bactericidal Efficacy

Elizabeth Ladd, Amir Sheikhi, Na Li, Theo Van de Ven and Ashok Kakkar

Molecules, 2017, 22, 868
DOI: 10.3390/molecules22060868

Antibacterial and hemolytic activity of cationic polymer-vancomycin conjugates

İlayda Acaroğlu Degitz, Berk Hakkı Gazioğlu, Mehmet Burak Aksu, Seyda Malta, Ali Demir Sezer and Tarık Eren

European Polymer Journal, 2020, 141, 110084
DOI: 10.1016/j.eurpolymj.2020.110084

Synthesis, photophysical and antimicrobial activity of new water soluble ammonium quaternary benzanthrone in solution and in polylactide film

Desislava Staneva, Evgenia Vasileva-Tonkova, Mohamad Saleh I. Makki, Tariq Rashad Sobahi, Reda Mohamed Abdеl-Rahman, Abdullah M. Asiri and Ivo Grabchev

Journal of Photochemistry and Photobiology B: Biology, 2015, 143, 44
DOI: 10.1016/j.jphotobiol.2014.12.024

Аntimicrobial and anticancer activity of new poly(propyleneamine) metallodendrimers

Ivo Grabchev, Desislava Staneva, Evgenia Vasileva-Tonkova, Radostina Alexandrova, Michela Cangiotti, Alberto Fattori and Maria Francesca Ottaviani

J Polym Res, 2017, 24
DOI: 10.1007/s10965-017-1387-0

Effect of Cavity Cleanser With Long-Term Antibacterial and Anti-Proteolytic Activities on Resin–Dentin Bond Stability

Yaping Gou, Wei Jin, Yanning He, Yu Luo, Ruirui Si, Yuan He, Zhongchi Wang, Jing Li and Bin Liu

Front. Cell. Infect. Microbiol., 2021, 11
DOI: 10.3389/fcimb.2021.784153

Polymeric drugs: Advances in the development of pharmacologically active polymers

Jing Li, Fei Yu, Yi Chen and David Oupický

Journal of Controlled Release, 2015, 219, 369
DOI: 10.1016/j.jconrel.2015.09.043

Developments in Treatment Methodologies Using Dendrimers for Infectious Diseases

Nina Filipczak, Satya Siva Kishan Yalamarty, Xiang Li, Farzana Parveen and Vladimir Torchilin

Molecules, 2021, 26, 3304
DOI: 10.3390/molecules26113304

Poly(propylenamine) dendrimers modified with 4-amino-1,8-naphthalimide: Synthesis, characterization and in vitro microbiological tests of their Cu(II) and Zn(II) complexes

Ivo Grabchev, Stanislava Yordanova, Evgenia Vasileva-Tonkova, Paula Bosch and Stanimir Stoyanov

Inorganica Chimica Acta, 2015, 438, 179
DOI: 10.1016/j.ica.2015.09.010

Nanocarriers for antibiotics: A promising solution to treat intracellular bacterial infections

Nadia Abed and Patrick Couvreur

International Journal of Antimicrobial Agents, 2014, 43, 485
DOI: 10.1016/j.ijantimicag.2014.02.009