John W. Blunt, Brent R. Copp, Wan-Ping Hu, Murray H. G. Munro, Peter T. Northcote and Mich?le R. Prinsep

Nat. Prod. Rep., 2007, 24, 31
DOI: 10.1039/b603047p

LOX‐Induced Lipid Peroxidation Mechanism Responsible for the Detrimental Effect of Marine Diatoms on Zooplankton Grazers

Angelo Fontana, Giuliana d'Ippolito, Adele Cutignano, Giovanna Romano, Nadia Lamari, Alexia Massa Gallucci, Guido Cimino, Antonio Miralto and Adrianna Ianora

ChemBioChem, 2007, 8, 1810
DOI: 10.1002/cbic.200700269

Oxylipin production during a mesocosm bloom of Skeletonema marinoi

Andrea Gerecht, Ylenia Carotenuto, Adrianna Ianora, Giovanna Romano, Angelo Fontana, Giuliana d'Ippolito, Hans H. Jakobsen and Jens C. Nejstgaard

Journal of Experimental Marine Biology and Ecology, 2013, 446, 159
DOI: 10.1016/j.jembe.2013.05.014

Silencing of a Pseudo‐nitzschia arenysensis lipoxygenase transcript leads to reduced oxylipin production and impaired growth

Valeria Sabatino, Ida Orefice, Pina Marotta, Luca Ambrosino, Maria Luisa Chiusano, Giuliana d'Ippolito, Giovanna Romano, Angelo Fontana and Maria Immacolata Ferrante

New Phytologist, 2022, 233, 809
DOI: 10.1111/nph.17739

Lipid and Fatty Acid Composition of Diatoms Revisited: Rapid Wound‐Activated Change of Food Quality Parameters Influences Herbivorous Copepod Reproductive Success

Thomas Wichard, Andrea Gerecht, Maarten Boersma, Serge A. Poulet, Karen Wiltshire and Georg Pohnert

ChemBioChem, 2007, 8, 1146
DOI: 10.1002/cbic.200700053

Exploring Valuable Lipids in Diatoms

Zhiqian Yi, Maonian Xu, Xiaxia Di, Sigurdur Brynjolfsson and Weiqi Fu

Front. Mar. Sci., 2017, 4
DOI: 10.3389/fmars.2017.00017

Re-shaping marine plankton communities: effects of diatom oxylipins on copepods and beyond

Ennio Russo, Adrianna Ianora and Ylenia Carotenuto

Mar Biol, 2019, 166
DOI: 10.1007/s00227-018-3456-2

Unveiling the anti-proliferative and pro-thermogenic activity of Staurosirella pinnata (Bacillariophyta) bioproducts

Saverio Savio, Riccardo Turchi, Marianna Carbone, Maria Letizia Ciavatta, Daniele Lettieri-Barbato, Katia Aquilano, Carlo Rodolfo and Roberta Congestri

Algal Research, 2024, 78, 103393
DOI: 10.1016/j.algal.2024.103393

PLASTICITY OF OXYLIPIN METABOLISM AMONG CLONES OF THE MARINE DIATOM SKELETONEMA MARINOI (BACILLARIOPHYCEAE)1

Andrea Gerecht, Giovanna Romano, Adrianna Ianora, Giuliana d’Ippolito, Adele Cutignano and Angelo Fontana

Journal of Phycology, 2011, 47, 1050
DOI: 10.1111/j.1529-8817.2011.01030.x

Fatty acid isotopic fractionation in the diatom Chaetoceros muelleri

Marine Remize, Frédéric Planchon, Ai Ning Loh, Fabienne Le Grand, Margaux Mathieu-Resuge, Antoine Bideau, Rudolph Corvaisier, Aswani Volety and Philippe Soudant

Algal Research, 2021, 54, 102164
DOI: 10.1016/j.algal.2020.102164

Different Responses to Heat Shock Stress Revealed Heteromorphic Adaptation Strategy of Pyropia haitanensis (Bangiales, Rhodophyta)

Qijun Luo, Zhenggang Zhu, Zhujun Zhu, Rui Yang, Feijian Qian, Haimin Chen, Xiaojun Yan and Sue Cotterill

PLoS ONE, 2014, 9, e94354
DOI: 10.1371/journal.pone.0094354

First Morphological and Molecular Evidence of the Negative Impact of Diatom-Derived Hydroxyacids on the Sea UrchinParacentrotus lividus

Stefano Varrella, Giovanna Romano, Nadia Ruocco, Adrianna Ianora, Matt G. Bentley and Maria Costantini

Toxicol. Sci., 2016, 151, 419
DOI: 10.1093/toxsci/kfw053

Nitric oxide mediates oxylipin production and grazing defense in diatoms

Matthew D. Johnson, Bethanie R. Edwards, David J. Beaudoin, Benjamin A. S. Van Mooy and Assaf Vardi

Environmental Microbiology, 2020, 22, 629
DOI: 10.1111/1462-2920.14879

Biosynthetic intermediates and stereochemical aspects of aldehyde biosynthesis in the marine diatom Thalassiosira rotula

Giuliana d’Ippolito, Adele Cutignano, Sara Tucci, Giovanna Romano, Guido Cimino and Angelo Fontana

Phytochemistry, 2006, 67, 314
DOI: 10.1016/j.phytochem.2005.11.012

Maternal and neonate diatom diets impair development and sex differentiation in the copepod Temora stylifera

Ylenia Carotenuto, Adrianna Ianora and Antonio Miralto

Journal of Experimental Marine Biology and Ecology, 2011, 396, 99
DOI: 10.1016/j.jembe.2010.10.012

New oxylipins produced at the end of a diatom bloom and their effects on copepod reproductive success and gene expression levels

Chiara Lauritano, Giovanna Romano, Vittoria Roncalli, Angela Amoresano, Carolina Fontanarosa, Mauro Bastianini, Federica Braga, Ylenia Carotenuto and Adrianna Ianora

Harmful Algae, 2016, 55, 221
DOI: 10.1016/j.hal.2016.03.015

Density-dependent oxylipin production in natural diatom communities: possible implications for plankton dynamics

Ennio Russo, Giuliana d’Ippolito, Angelo Fontana, Diana Sarno, Domenico D’Alelio, Greta Busseni, Adrianna Ianora, Eric von Elert and Ylenia Carotenuto

The ISME Journal, 2020, 14, 164
DOI: 10.1038/s41396-019-0518-5

The Microalga Skeletonema marinoi Induces Apoptosis and DNA Damage in K562 Cell Line by Modulating NADPH Oxidase

Roberto Ciarcia, Consiglia Longobardi, Gianmarco Ferrara, Serena Montagnaro, Emanuela Andretta, Francesco Pagnini, Salvatore Florio, Lucianna Maruccio, Chiara Lauritano and Sara Damiano

Molecules, 2022, 27, 8270
DOI: 10.3390/molecules27238270

Oxylipin Diversity in the Diatom Family Leptocylindraceae Reveals DHA Derivatives in Marine Diatoms

Deepak Nanjappa, Giuliana D'Ippolito, Carmela Gallo, Adriana Zingone and Angelo Fontana

Marine Drugs, 2014, 12, 368
DOI: 10.3390/md12010368

Lipoxygenase Pathways in Diatoms: Occurrence and Correlation with Grazer Toxicity in Four Benthic Species

Nadia Ruocco, Genoveffa Nuzzo, Giuliana d’Ippolito, Emiliano Manzo, Angela Sardo, Adrianna Ianora, Giovanna Romano, Antonella Iuliano, Valerio Zupo, Maria Costantini and Angelo Fontana

Marine Drugs, 2020, 18, 66
DOI: 10.3390/md18010066

Chloroplastic Glycolipids Fuel Aldehyde Biosynthesis in the Marine Diatom Thalassiosira rotula

Adele Cutignano, Giuliana d'Ippolito, Giovanna Romano, Nadia Lamari, Guido Cimino, Ferdinando Febbraio, Roberto Nucci and Angelo Fontana

ChemBioChem, 2006, 7, 450
DOI: 10.1002/cbic.200500343

Molecular and Morphological Toxicity of Diatom-Derived Hydroxyacid Mixtures to Sea Urchin Paracentrotus lividus Embryos

Luisa Albarano, Nadia Ruocco, Adrianna Ianora, Giovanni Libralato, Loredana Manfra and Maria Costantini

Marine Drugs, 2019, 17, 144
DOI: 10.3390/md17030144

Oxidative Processes in the Australian Marine Sponge Plakinastrella clathrata: Isolation of Plakortolides with Oxidatively Modified Side Chains

Ken W. L. Yong, Lynette K. Lambert, Patricia Y. Hayes, James J. De Voss and Mary J. Garson

J. Nat. Prod., 2012, 75, 351
DOI: 10.1021/np200619q

Multiple Roles of Diatom-Derived Oxylipins within Marine Environments and Their Potential Biotechnological Applications

Nadia Ruocco, Luisa Albarano, Roberta Esposito, Valerio Zupo, Maria Costantini and Adrianna Ianora

Marine Drugs, 2020, 18, 342
DOI: 10.3390/md18070342

De novo transcriptome assembly of a lipoxygenase knock-down strain in the diatom Pseudo-nitzschia arenysensis

Pina Marotta, Valeria Sabatino, Luca Ambrosino, Marco Miralto and Maria Immacolata Ferrante

Sci Data, 2024, 11
DOI: 10.1038/s41597-024-03375-0

Low-Molecular-Weight Metabolites from Diatoms: Structures, Biological Roles and Biosynthesis

Valentin Stonik and Inna Stonik

Marine Drugs, 2015, 13, 3672
DOI: 10.3390/md13063672

Study of Synthesis Pathways of the Essential Polyunsaturated Fatty Acid 20:5n-3 in the Diatom Chaetoceros Muelleri Using 13C-Isotope Labeling

Marine Remize, Frédéric Planchon, Ai Ning Loh, Fabienne Le Grand, Antoine Bideau, Nelly Le Goic, Elodie Fleury, Philippe Miner, Rudolph Corvaisier, Aswani Volety and Philippe Soudant

Biomolecules, 2020, 10, 797
DOI: 10.3390/biom10050797

New trends in marine chemical ecology

A. Ianora, M. Boersma, R. Casotti, A. Fontana, J. Harder, F. Hoffmann, H. Pavia, P. Potin, S. A. Poulet and G. Toth

Estuaries and Coasts: J ERF, 2006, 29, 531
DOI: 10.1007/BF02784281

Configurational Assignment of Cyclic Peroxy Metabolites Provides an Insight into Their Biosynthesis: Isolation of Plakortolides, seco-Plakortolides, and Plakortones from the Australian Marine Sponge Plakinastrella clathrata

Ken W. L. Yong, James J. De Voss, John N. A. Hooper and Mary J. Garson

J. Nat. Prod., 2011, 74, 194
DOI: 10.1021/np100620x

Selective and context‐dependent effects of chemical stress across trophic levels at the basis of marine food webs

Christoph Mensens, Frederik De Laender, Colin R. Janssen, Frances Camille Rivera, Koen Sabbe and Marleen De Troch

Ecological Applications, 2018, 28, 1342
DOI: 10.1002/eap.1737

Autoinhibitory sterol sulfates mediate programmed cell death in a bloom-forming marine diatom

Carmela Gallo, Giuliana d’Ippolito, Genoveffa Nuzzo, Angela Sardo and Angelo Fontana

Nat Commun, 2017, 8
DOI: 10.1038/s41467-017-01300-1

Viral Infection Leads to a Unique Suite of Allelopathic Chemical Signals in Three Diatom Host–Virus Pairs

Bethanie R. Edwards, Kimberlee Thamatrakoln, Helen F. Fredricks, Kay D. Bidle and Benjamin A. S. Van Mooy

Marine Drugs, 2024, 22, 228
DOI: 10.3390/md22050228

15S‐Lipoxygenase metabolism in the marine diatom Pseudo‐nitzschia delicatissima

Giuliana D’Ippolito, Nadia Lamari, Marina Montresor, Giovanna Romano, Adele Cutignano, Andrea Gerecht, Guido Cimino and Angelo Fontana

New Phytologist, 2009, 183, 1064
DOI: 10.1111/j.1469-8137.2009.02887.x

Implementation in lipid extraction and analysis from phytoplankton: Skeletonema marinoi as case study

Ennio Russo, Ana Margarida Campos, Giuliana d'Ippolito, Emiliano Manzo, Ylenia Carotenuto, Angelo Fontana and Genoveffa Nuzzo

Marine Chemistry, 2021, 232, 103964
DOI: 10.1016/j.marchem.2021.103964

Specificity of Lipoxygenase Pathways Supports Species Delineation in the Marine Diatom Genus Pseudo-nitzschia

Nadia Lamari, Maria Valeria Ruggiero, Giuliana d’Ippolito, Wiebe H. C. F. Kooistra, Angelo Fontana, Marina Montresor and Tilmann Harder

PLoS ONE, 2013, 8, e73281
DOI: 10.1371/journal.pone.0073281

LIPOXYGENASE PRODUCTS IN MARINE DIATOMS: A CONCISE ANALYTICAL METHOD TO EXPLORE THE FUNCTIONAL POTENTIAL OF OXYLIPINS1

Adele Cutignano, Nadia Lamari, Giuliana d’ippolito, Emiliano Manzo, Guido Cimino and Angelo Fontana

Journal of Phycology, 2011, 47, 233
DOI: 10.1111/j.1529-8817.2011.00972.x

First identification of marine diatoms with anti-tuberculosis activity

Chiara Lauritano, Jesús Martín, Mercedes de la Cruz, Fernando Reyes, Giovanna Romano and Adrianna Ianora

Sci Rep, 2018, 8
DOI: 10.1038/s41598-018-20611-x

Chemistry of oxylipin pathways in marine diatoms

Angelo Fontana, Giuliana d'Ippolito, Adele Cutignano, Antonio Miralto, Adrianna Ianora, Giovanna Romano and Guido Cimino

Pure and Applied Chemistry, 2007, 79, 481
DOI: 10.1351/pac200779040481

Combined Effects of Diatom-Derived Oxylipins on the Sea Urchin Paracentrotus lividus

Roberta Esposito, Nadia Ruocco, Luisa Albarano, Adrianna Ianora, Loredana Manfra, Giovanni Libralato and Maria Costantini

IJMS, 2020, 21, 719
DOI: 10.3390/ijms21030719

Design and Synthesis of Pro-Apoptotic Compounds Inspired by Diatom Oxylipins

Giovanna Romano, Emiliano Manzo, Gian Russo, Giuliana D'Ippolito, Adele Cutignano, Maria Russo and Angelo Fontana

Marine Drugs, 2013, 11, 4527
DOI: 10.3390/md11114527

Toxigenic effects of diatoms on grazers, phytoplankton and other microbes: a review

Adrianna Ianora and Antonio Miralto

Ecotoxicology, 2010, 19, 493
DOI: 10.1007/s10646-009-0434-y

Diatom induction of reproductive failure in copepods: The effect of PUAs versus non volatile oxylipins

A. Barreiro, Y. Carotenuto, N. Lamari, F. Esposito, G. D'Ippolito, A. Fontana, G. Romano, A. Ianora, A. Miralto and C. Guisande

Journal of Experimental Marine Biology and Ecology, 2011, 401, 13
DOI: 10.1016/j.jembe.2011.03.007

Two Isomeric C16 Oxo-Fatty Acids from the Diatom Chaetoceros karianus Show Dual Agonist Activity towards Human Peroxisome Proliferator-Activated Receptors (PPARs) α/γ

Angel Moldes-Anaya, Thomas Sæther, Silvio Uhlig, Hilde Nebb, Terje Larsen, Hans Eilertsen and Steinar Paulsen

Marine Drugs, 2017, 15, 148
DOI: 10.3390/md15060148

Low reproductive success for copepods during a bloom of the non‐aldehyde‐producing diatom Cerataulina pelagica in the North Adriatic Sea

Adrianna Ianora, Raffaella Casotti, Mauro Bastianini, Christophe Brunet, Giuliana D’Ippolito, Francesco Acri, Angelo Fontana, Adele Cutignano, Jefferson T. Turner and Antonio Miralto

Marine Ecology, 2008, 29, 399
DOI: 10.1111/j.1439-0485.2008.00226.x

RNA-Seq and differential gene expression analysis in Temora stylifera copepod females with contrasting non-feeding nauplii survival rates: an environmental transcriptomics study

Ennio Russo, Chiara Lauritano, Giuliana d’Ippolito, Angelo Fontana, Diana Sarno, Eric von Elert, Adrianna Ianora and Ylenia Carotenuto

BMC Genomics, 2020, 21
DOI: 10.1186/s12864-020-07112-w

Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae

Valerie J. Smith, Andrew P. Desbois and Elisabeth A. Dyrynda

Marine Drugs, 2010, 8, 1213
DOI: 10.3390/md8041213

Impact of the diatom oxylipin 15S-HEPE on the reproductive success of the copepod Temora stylifera

Adrianna Ianora, Giovanna Romano, Ylenia Carotenuto, Francesco Esposito, Vittoria Roncalli, Isabella Buttino and Antonio Miralto

Hydrobiologia, 2011, 666, 265
DOI: 10.1007/s10750-010-0420-7

Determination of Lipid Hydroperoxides in Marine Diatoms by the FOX2 Assay

Ida Orefice, Andrea Gerecht, Giuliana D'Ippolito, Angelo Fontana, Adrianna Ianora and Giovanna Romano

Marine Drugs, 2015, 13, 5767
DOI: 10.3390/md13095767

Fatty Acids Derivatives From Eukaryotic Microalgae, Pathways and Potential Applications

Martina Blasio and Sergio Balzano

Front. Microbiol., 2021, 12
DOI: 10.3389/fmicb.2021.718933

First evidence of anticancer and antimicrobial activity in Mediterranean mesopelagic species

Chiara Lauritano, Kevin A. Martínez, Pietro Battaglia, Antonia Granata, Mercedes de la Cruz, Bastien Cautain, Jesús Martín, Fernando Reyes, Adrianna Ianora and Letterio Guglielmo

Sci Rep, 2020, 10
DOI: 10.1038/s41598-020-61515-z

Discovery and Anti-Inflammatory Activity of a Cyanobacterial Fatty Acid Targeting the Keap1/Nrf2 Pathway

Fatma H. Al-Awadhi, Emily F. Simon, Na Liu, Ranjala Ratnayake, Valerie J. Paul and Hendrik Luesch

Marine Drugs, 2023, 21, 553
DOI: 10.3390/md21110553