Issue 23, 2022

Recent advances in thiolation via sulfur electrophiles

Abstract

Umpolung of thiols has become a common strategy for the synthesis of various S-containing compounds and thus a series of sulfur electrophiles have been designed and applied for diverse thiolations. To meet different demands for the incorporation of thio groups with regio- and stereoselectivity, new catalyst systems and methodologies based on the utility of sulfur electrophiles have been well developed. In this review, achievements on various thiolation methodologies with sulfur electrophiles have been summarized, mainly including thiofunctionalization of alkenes or alkynes, insertion of carbene precursors, C–S cross coupling and electrophilic substitution, aiming to give a comprehensive insight into the application of electrophilic sulfur reagents.

Graphical abstract: Recent advances in thiolation via sulfur electrophiles

Article information

Article type
Review Article
Submitted
13 Eyl 2022
Accepted
10 Eki 2022
First published
12 Eki 2022

Org. Chem. Front., 2022,9, 6684-6707

Recent advances in thiolation via sulfur electrophiles

Y. Wei, W. Gao, H. Chang and X. Jiang, Org. Chem. Front., 2022, 9, 6684 DOI: 10.1039/D2QO01447E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements