Issue 1, 2018

Rhodium-catalyzed intermolecular C(sp3)–H amination in a purely aqueous system

Abstract

An efficient Rh-catalyzed intermolecular C(sp3)–H amination in a purely aqueous system is developed for the first time. This methodology features environmental benignity, broad substrate scope and versatility in late-stage functionalization of several biologically important molecules. Such an oxidation protocol provides easy access to various aliphatic amine derivatives in an efficient and sustainable manner.

Graphical abstract: Rhodium-catalyzed intermolecular C(sp3)–H amination in a purely aqueous system

Supplementary files

Article information

Article type
Communication
Submitted
19 Eki 2017
Accepted
27 Kas 2017
First published
28 Kas 2017

Green Chem., 2018,20, 113-117

Rhodium-catalyzed intermolecular C(sp3)–H amination in a purely aqueous system

X. Lu, Y. Shi and F. Zhong, Green Chem., 2018, 20, 113 DOI: 10.1039/C7GC03149A

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