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Counterions always coexist with charged peptides in charge transport processes, which are excellent candidate components for tunable molecular electronic devices. Here, we introduced hard–soft acid base theory to analyze the counterion-modulated peptide charge transport. We demonstrate that the peptide charge transport is improved by enhanced peptide-counterion interactions.

Graphical abstract: Hard–soft chemistry guides the adaptable charge transport in lysine-doped heptapeptide junctions

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