Issue 6, 2018

Copper-catalyzed three-component phosphorylation–peroxidation of alkenes

Abstract

A copper-catalyzed phosphorylation–peroxidation of alkenes has been developed. The three-component protocol provides practical access to multisubstituted β-phosphoryl peroxides by the reactions of P(O)–H compounds, alkenes and tert-butyl hydroperoxide (TBHP). The obtained β-phosphoryl peroxides can be applied to the synthesis of β-phosphoryl epoxides by using lithium bis(trimethylsilyl)amide (LHMDS) as a base.

Graphical abstract: Copper-catalyzed three-component phosphorylation–peroxidation of alkenes

Supplementary files

Article information

Article type
Research Article
Submitted
22 Kas 2017
Accepted
20 Ara 2017
First published
21 Ara 2017

Org. Chem. Front., 2018,5, 972-976

Copper-catalyzed three-component phosphorylation–peroxidation of alkenes

Y. Chen, Y. Chen, S. Lu and Z. Li, Org. Chem. Front., 2018, 5, 972 DOI: 10.1039/C7QO01045A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements