The purpose of this study is to synthesize novel N,2,6-trisubstituted 1H-benzimidazole derivatives and evaluation of their antibacterial, antifungal, and anticancer activities as well as to study their mechanism of action.
Chlorophenylamino-s-triazine derivatives were synthesized and tested for anticancer activity against MCF7 and C26 cells. Promising compounds showed therapeutic potential and favorable drug-like properties via in silico docking and ADMET analyses.
This study aimed to synthesize symmetrical phenylamino-s-triazine derivatives with one aromatic amine and two hexagonal saturated cyclic amines and evaluate their anticancer activity. The potential derivatives have been investigated in silico.
Fe3O4@SiO2@Mn-complex was successfully prepared and utilized in the synthesis of biologically active pyridopyrimidinones in an aqueous medium, providing environmentally friendly conditions.
New carbohydrate-based ionic liquids are characterized, towards their thermal stability, biocompatibility and antimicrobial behavior. The results led to structure–property relationships and higher cell viabilities than most commercial ionic liquids.