l-Theanine attenuates heat stress-induced proteotoxicity and alterations in carbohydrate and lipid metabolismviaheat shock factor 1

Ling Lin, Shumin Han, Zhihua Gong, Furong Ding, Zhonghua Liu and Wenjun Xiao

Food Funct., 2023, 14, 6172
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l-theanine: From tea leaf to trending supplement – does the science match the hype for brain health and relaxation?

Roderick Dashwood and Francesco Visioli

Nutrition Research, 2025, 134, 39
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Alzheimer’s disease: an integrative bioinformatics and machine learning analysis reveals glutamine metabolism-associated gene biomarkers

Naifei Xing, Jingwei Yan, Rong Gao, Aihua Zhang, Huiyan He, Man Zheng and Guojing Li

BMC Pharmacol Toxicol, 2025, 26
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L-Theanine: A Unique Functional Amino Acid in Tea (Camellia sinensis L.) With Multiple Health Benefits and Food Applications

Ming-Yue Li, Hong-Yan Liu, Ding-Tao Wu, Ahmad Kenaan, Fang Geng, Hua-Bin Li, Anil Gunaratne, Hang Li and Ren-You Gan

Front. Nutr., 2022, 9
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Regulatory Effects and Mechanisms of L-Theanine on Neurotransmitters via Liver–Brain Axis Under a High Protein Diet

Wei Xu, Yuxin Song, Wenjun Xiao and Zhihua Gong

Mol Neurobiol, 2024, 61, 783
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Targeted intervention of natural medicinal active ingredients and traditional Chinese medicine on epigenetic modification: Possible strategies for prevention and treatment of atherosclerosis

Wei Wang, Han Li, Ying Shi, Jing Zhou, Ghulam Jilany Khan, Juan Zhu, Fawang Liu, Hong Duan, Lili Li and Kefeng Zhai

Phytomedicine, 2024, 122, 155139
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Glutamine metabolism-related genes and immunotherapy in nonspecific orbital inflammation were validated using bioinformatics and machine learning

Zixuan Wu, Na Li, Yuan Gao, Liyuan Cao, Xiaolei Yao and Qinghua Peng

BMC Genomics, 2024, 25
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L-theanine regulates the immune function of SD rats fed high-protein diets through the FABP5/IL-6/STAT3/PPARα pathway

Yangling Zhang, Yuxin Song, Jiao Zhang, Lanlan Li, Lin He, Jiahui Bo, Zhihua Gong and Wenjun Xiao

Food and Chemical Toxicology, 2023, 181, 114095
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L-Theanine and Immunity: A Review

Shuna Chen, Jiaxin Kang, Huanqing Zhu, Kaixi Wang, Ziyi Han, Leyu Wang, Junsheng Liu, Yuanyuan Wu, Puming He, Youying Tu and Bo Li

Molecules, 2023, 28, 3846
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Protective Effect of l-Theanine on Cyclophosphamide-Induced Testicular Toxicity in Mice

Yulong Ye, Chunyan Fang, Lanying Li, Dongna Liu, Yingchun Wang, Fan Huang, Xuejiao Gong, Yaqiong Xu, Yu Yao, Shanrong Ye, Dejian Feng and Fan Luo

J. Agric. Food Chem., 2023, 71, 8050
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L‐Theanine Ameliorates Doxorubicin‐Induced Ovarian Toxicity by Reducing Endoplasmic Reticulum Stress

Meltem Arıkan Malkoç, Serap Özer Yaman, Esin Yuluğ, Semanur Işık and Birgül Kural

Food Science & Nutrition, 2025, 13
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Food preference-based screening method for identification of effectors of substance use disorders using Caenorhabditis elegans

Aaron Taehwan Kim, Sida Li, Yoo Kim, Young-Jai You and Yeonhwa Park

Life Sciences, 2024, 345, 122580
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A novel Alzheimer’s disease prognostic signature: identification and analysis of glutamine metabolism genes in immunogenicity and immunotherapy efficacy

Zixuan Wu, Ping Liu, Baisheng Huang, Sisi Deng, Zhenyan Song, Xindi Huang, Jing Yang and Shaowu Cheng

Sci Rep, 2023, 13
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Exploring the molecular mechanisms and therapeutic benefits of L-theanine in counteracting inflammation

Satarupa Deb and Anupom Borah

PharmaNutrition, 2024, 30, 100419
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L‐Theanine Mitigates the Harmful Effects of Excess High‐Protein Diet in Rats by Regulating Protein Metabolism

Ling Lin, Jiao Zhang, Lin He, Lanlan Li, Yuxin Song, Wenjun Xiao and Zhihua Gong

Molecular Nutrition Food Res, 2023, 67
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Bioinformatics and machine learning were used to validate glutamine metabolism-related genes and immunotherapy in osteoporosis patients

Lei Wang, Chaosheng Deng, Zixuan Wu, Kaidong Zhu and Zhenguo Yang

J Orthop Surg Res, 2023, 18
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L-theanine improves intestinal barrier functions by increasing tight junction protein expression and attenuating inflammatory reaction in weaned piglets

Xiaoling Chen, Lili Chen, Gang Jia, Hua Zhao, Guangmang Liu and Zhiqing Huang

Journal of Functional Foods, 2023, 100, 105400
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Glutamine metabolism genes prognostic signature for stomach adenocarcinoma and immune infiltration: potential biomarkers for predicting overall survival

Hui Li, Zixuan Wu, Yu Zhang, Xiaohui Lu and Lili Miao

Front. Oncol., 2023, 13
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Potential role of green tea amino acid l‐theanine in the activation of innate immune response by enhancing expression of cytochrome b558 responsible for the reactive oxygen species‐generating ability of leukocytes

Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha and Futoshi Kuribayashi

Microbiology and Immunology, 2022, 66, 342
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Protective Effect and Mechanism of L‐Theanine on Acute Alcoholic Liver Injury in Mice

Meng‐Yuan Liu, Kai‐Hang Xu, Sha Liu and Wen‐Jun Xiao

Molecular Nutrition Food Res, 2024, 68
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How does l-theanine treatment affect the levels of serum and hippocampal BDNF, insulin and adipocytokines in diabetic rats?

Hamed Hajizadeh Tekmeh, Birgul Vanizor Kural, Sevil Kör, Meltem Arıkan Malkoç, Esin Yuluğ, Abdulkadir Kutlu, İsmail Abidin and Asım Orem

Biochemical and Biophysical Research Communications, 2023, 667, 95
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Glutamatergic and GABAergic metabolite levels in Alzheimer’s disease: a systematic review and meta-analysis

Rasoul Ebrahimi, Sana Mohammad Soltani, Mohammad Mahdi Masouri, Mojtaba Seifi, Kiana Ghafourian and Shokoofe Noori

BMC Neurol, 2025, 25
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Integrative bioinformatics and machine learning approach unveils potential biomarkers linking coronary atherosclerosis and glutamine metabolism-associated gene

Shiwei Wang, Man Zheng and Jing Yang

J Cardiothorac Surg, 2025, 21
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L-Theanine Modulates Intestine-Specific Immunity by Regulating the Differentiation of CD4+ T Cells in Ovalbumin-Sensitized Mice

Qing-Yun Qu, Xian-Ying Song, Ling Lin, Zhi-Hua Gong, Wei Xu and Wen-Jun Xiao

J. Agric. Food Chem., 2022, 70, 14851
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L-theanine prevents ulcerative colitis by regulating the CD4+ T cell immune response through the gut microbiota and its metabolites

Wei Xu, Aoxiang Liu, Zhihua Gong and Wenjun Xiao

The Journal of Nutritional Biochemistry, 2025, 139, 109845
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Microbial composition, bioactive compounds, and sensory evaluation of Kombucha prepared with green tea and black tea

Jiayi Yuan, Qing Nie, Wenjing Pan, Zhonghua Liu, Jianhua Wu, Zhusheng Liu and Shuxian Cai

B, 2025, 5, 0
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Green tea: Current trends and prospects in nutraceutical and pharmaceutical aspects

Anupam Sarma, Ratnali Bania and Malay K. Das

Journal of Herbal Medicine, 2023, 41, 100694
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