Issue 35, 2021

The biology and total syntheses of bisbenzylisoquinoline alkaloids

Abstract

This mini-review provides a concise overview of the biosynthetic pathway and pharmacology of bisbenzylisoquinoline alkaloid (bisBIA) natural products. Additional emphasis is given to the methodologies in the total syntheses of both simpler acyclic diaryl ether dimers and their macrocyclic counterparts bearing two diaryl ether linkages.

Graphical abstract: The biology and total syntheses of bisbenzylisoquinoline alkaloids

Article information

Article type
Review Article
Submitted
26 เม.ย. 2564
Accepted
21 ก.ค. 2564
First published
17 ส.ค. 2564

Org. Biomol. Chem., 2021,19, 7535-7543

The biology and total syntheses of bisbenzylisoquinoline alkaloids

V. K. Nguyen and Kevin. G. M. Kou, Org. Biomol. Chem., 2021, 19, 7535 DOI: 10.1039/D1OB00812A

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