Orally administered octacosanol improves liver insulin resistance in high-fat diet-fed mice through the reconstruction of the gut microbiota structure and inhibition of the TLR4/NF-κB inflammatory pathway

Yin-Yi Ding, Yumeng Fang, Yuxiang Pan, Jinchi Lan, Tao Xu, Wanyue Zhang, Huijuan Mao, Zhenyu Gu, Xi Chen and Qing Shen

Food Funct., 2023, 14, 769
DOI: 10.1039/D2FO02463B

Lactobacillus reuteri JCM 1112 ameliorates chronic acrylamide-induced glucose metabolism disorder via the bile acid–TGR5–GLP-1 axis and modulates intestinal oxidative stress in mice

Zonghao Yue, Feiyue Zhao, Yuqi Guo, Yidan Zhang, Yanjuan Chen, Le He and Lili Li

Food Funct., 2024, 15, 6450
DOI: 10.1039/D4FO01061B

Latilactobacillus sakei QC9 alleviates hyperglycaemia in high-fat diet and streptozotocin-induced type 2 diabetes mellitus mice via the microbiota–gut–liver axis

Mengling Chen, Pengyuan Pan, Hongyan Zhang, Rao Li, Dayong Ren and Bin Jiang

Food Funct., 2024, 15, 8008
DOI: 10.1039/D4FO02316A

In vivoandin silicostudy of antioxidant and anti-inflammatory effects on the liver-spleen axis of microencapsulated brewers’ spent grain peptides

María E. Oliva, Raúl E. Cian, María del Rosario Ferreira, Antonela G. Garzón, Silvina R. Drago and María E. D'Alessandro

Food Funct., 2023, 14, 5290
DOI: 10.1039/D2FO04104A

Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats

Yaping Liu, Haoyue Huang, Ze Xu, Yuan Xue, Dongdong Zhang, Yujing Zhang, Wenjie Li and Xing Li

Food Funct., 2022, 13, 2693
DOI: 10.1039/D1FO04164A

Elucidation of the interaction effect between dietary fiber and bound polyphenol components on the anti-hyperglycemic activity of tea residue dietary fiber

Hairong Huang, Jiajun Chen, Xiaobo Hu, Yi Chen, Jianhua Xie, Tianxiang Ao, Hui Wang, Jiayan Xie and Qiang Yu

Food Funct., 2022, 13, 2710
DOI: 10.1039/D1FO03682C

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei and Yanhui Lu

iMetaOmics, 2025, 2
DOI: 10.1002/imo2.70020

Inhibitory Effect of Lactobacillus delbrueckii subsp. bulgaricus KSFY07 on Kappa-Carrageenan-Induced Thrombosis in Mice and the Regulation of Oxidative Damage

Pan Wang, Fang Tan, Jianfei Mu, Hongjiang Chen, Xin Zhao, Yanan Xu and Victor Garcia

Cardiovascular Therapeutics, 2022, 2022, 1
DOI: 10.1155/2022/4415876

Dityrosine Aggravates Hepatic Insulin Resistance in Obese Mice by Altering Gut Microbiota and the LPS/TLR4/NF‐κB Inflammatory Pathway

Yin‐Yi Ding, Jinchi Lan, Yumeng Fang, Yuxiang Pan, Zhenyu Gu, Jing Xue, Ying Yang, Mengqi Jiang, Yujun Ge and Qing Shen

Molecular Nutrition Food Res, 2023, 67
DOI: 10.1002/mnfr.202300373

The Role and Mechanism of Probiotics Supplementation in Blood Glucose Regulation: A Review

Xinyu Shen, Chunmin Ma, Yang Yang, Xiaofei Liu, Bing Wang, Yan Wang, Guang Zhang, Xin Bian and Na Zhang

Foods, 2024, 13, 2719
DOI: 10.3390/foods13172719

Effects of Bcl-2 protein molecules and IκB kinase on the cell death of glioma cells: a study based on the chemical molecular extract of Erigeron breviscapus

Hanghang Du, Haofeng Xiong, Shi Zeng and Fei Chen

International Journal of Biological Macromolecules, 2025, 311, 144070
DOI: 10.1016/j.ijbiomac.2025.144070

The Enteric Glia and Its Modulation by the Endocannabinoid System, a New Target for Cannabinoid-Based Nutraceuticals?

Laura López-Gómez, Agata Szymaszkiewicz, Marta Zielińska and Raquel Abalo

Molecules, 2022, 27, 6773
DOI: 10.3390/molecules27196773

Lactic acid bacteria in Asian fermented foods and their beneficial roles in human health

Hyunok Doo, Jinok Kwak, Gi Beom Keum, Sumin Ryu, Yejin Choi, Juyoun Kang, Haram Kim, Yeongjae Chae, Sheena Kim, Hyeun Bum Kim and Ju-Hoon Lee

Food Sci Biotechnol, 2024, 33, 2021
DOI: 10.1007/s10068-024-01634-9

Integrated 16S rRNA sequencing and nontargeted metabolomics analysis to reveal the mechanisms of Yu-Ye Tang on type 2 diabetes mellitus rats

Ziang Ma, Wenjuan Sun, Lixin Wang, Yuansong Wang, Baochao Pan, Xiuhai Su, Hanzhou Li, Hui Zhang, Shuquan Lv and Hongwu Wang

Front. Endocrinol., 2023, 14
DOI: 10.3389/fendo.2023.1159707

Anti‐Obesity Effects of Leuconostoc mesenteroides 4‐Fermented Lemon Peel Filtrate on HFD‐Induced Obese Mice via NFκB/ PPAR‐γ Pathway

Xianrong Zhou, Yang Fan, Jia Liu, Ruokun Yi, Yongpeng He, Xin Zhao and Lujun Chen

Food Science & Nutrition, 2025, 13
DOI: 10.1002/fsn3.70039

Baihu renshen decoction ameliorates type 2 diabetes mellitus in rats through affecting gut microbiota enhancing gut permeability and inhibiting TLR4/NF-κB-mediated inflammatory response

Bin Yao, Baochao Pan, Tian Tian, Xiuhai Su, Shufang Zhang, Hanzhou Li, Wendong Li, Yuansong Wang, Shuquan Lv and Zhaiyi Zhang

Front. Cell. Infect. Microbiol., 2022, 12
DOI: 10.3389/fcimb.2022.1051962

Isolation, Characterization, Chemical Profiling and Evaluation of Antidiabetic and Antioxidant Potential of Innula cappa (Buch.-Ham. ex D. Don) DC Leaves in Alloxan-Induced Type 2 Diabetic Mice

Shahid Rahman, Gul Jan and Farzana Gul Jan

Natural Product Communications, 2024, 19
DOI: 10.1177/1934578X241306064

Syzygium zeylanicum (L.) DC. polyphenols exhibit anti-diabetic activity by modulation of ACC1, SGLT1, and GLP-1 genes and restoration of gut microbiota in overfeeding and high glucose exposure-induced diabetic zebrafish

Minh-Trung Nguyen, Thi-Bich-Huyen Bui, Van-Hung Pham, Minh-Dinh Tran and Quang-Vinh Nguyen

Journal of Functional Foods, 2024, 112, 105921
DOI: 10.1016/j.jff.2023.105921

Attenuation of Hyperglycemia in Diabetic Rats Assisted by Immobilized Probiotic in Sodium Alginate

José J. Arriaga-Morales, Cynthia Ordaz-Pichardo, Roberto Castro‑Muñoz and Enrique Durán-Páramo

Probiotics & Antimicro. Prot., 2024, 16, 2218
DOI: 10.1007/s12602-023-10166-3

The Application and Research of Probiotics in the Treatment of Diabetes

Zhe Sun and Chao Dong

WJIMT, 2024, 7, 145
DOI: 10.53469/wjimt.2024.07(05).18

Precision Microbiome Modulation: Exploring Lactobacillus spp. as A Targeted Strategy for Type 2 Diabetes Management

Ann Sze Cheah, Ji Wei Tan, Faizul Jaafar and Wendy Wai Yeng Yeo

Curr Nutr Rep, 2026, 15
DOI: 10.1007/s13668-026-00739-3

Fucoidan ameliorates glucose metabolism by the improvement of intestinal barrier and inflammatory damage in type 2 diabetic rats

Yaping Liu, Ze Xu, Haoyue Huang, Yuan Xue, Dongdong Zhang, Yujing Zhang, Wenjie Li and Xing Li

International Journal of Biological Macromolecules, 2022, 201, 616
DOI: 10.1016/j.ijbiomac.2022.01.102

Health-Promoting and Functional Properties of Fermented Milk Beverages with Probiotic Bacteria in the Prevention of Civilization Diseases

Milena Alicja Stachelska, Piotr Karpiński and Bartosz Kruszewski

Nutrients, 2024, 17, 9
DOI: 10.3390/nu17010009

Gut bacteria: an etiological agent in human pathological conditions

Md Minarul Islam, Nasir Uddin Mahbub, Seong-Tshool Hong and Hea-Jong Chung

Front. Cell. Infect. Microbiol., 2024, 14
DOI: 10.3389/fcimb.2024.1291148

Lactobacillus reuteri TISTR 2736 alleviates type 2 diabetes in rats via the hepatic IRS1/PI3K/AKT signaling pathway by mitigating oxidative stress and inflammatory mediators

Kamonthip Pakaew, Pennapa Chonpathompikunlert, Navinee Wongmanee, Worarat Rojanaverawong, Jaruwan Sitdhipol, Punnathorn Thaveethaptaikul, Natthawut Charoenphon and Wanthanee Hanchang

Eur J Nutr, 2025, 64
DOI: 10.1007/s00394-024-03529-1

Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 administration to Long–Evans rats has interactive effects with sex and diet on anxiety-related feeding behaviors and specific endocrine outcomes

Elizabeth M. Myles, M. Elizabeth O’Leary, Isaac D. Romkey, Sara I. Hamm, Laura Dauphinee, Amanda Piano, Stéphane Bronner and Tara S. Perrot

Physiology & Behavior, 2025, 300, 115030
DOI: 10.1016/j.physbeh.2025.115030

Slowly Digestible Carbohydrate Diet Ameliorates Hyperglycemia and Hyperlipidemia in High-Fat Diet/Streptozocin-Induced Diabetic Mice

Yu-Zhong Chen, Jia Gu, Wei-Ting Chuang, Ya-Fang Du, Lin Zhang, Meng-Lan Lu, Jia-Ying Xu, Hao-Qiu Li, Yan Liu, Hao-Tian Feng, Yun-Hong Li and Li-Qiang Qin

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.854725

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Nima Montazeri-Najafabady

Probiotics & Antimicro. Prot., 2025
DOI: 10.1007/s12602-025-10815-9

Lactobacillus plantarum HFY05 Attenuates Carrageenan-Induced Thrombosis in Mice by Regulating NF-κB Pathway-Associated Inflammatory Responses

Shi Zeng, Ruokun Yi, Fang Tan, Peng Sun, Qiang Cheng and Xin Zhao

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.813899

Lactiplantibacillus plantarum Ln4 attenuates streptozotocin and high-fat diet-induced Type-2 diabetes

Rachit Sood, Kritika, Sanjay and Hae-Jeung Lee

Journal of Functional Foods, 2026, 138, 107219
DOI: 10.1016/j.jff.2026.107219

Probiotics intervention for type 2 diabetes mellitus therapy: a review from proposed mechanisms to future prospects

Xue Li, Yongjun Xia, Xin Song, Zhiqiang Xiong, Lianzhong Ai and Guangqiang Wang

Critical Reviews in Food Science and Nutrition, 2025, 65, 4457
DOI: 10.1080/10408398.2024.2387765

Administration of Bifidobacterium animalis Subsp. lactis BLa80 and Lactobacillus acidophilus LA85 Improved Hyperglycemia and Modulated Gut Microbiota in Type 2 Diabetic Mice

Mingming Zhu, Lvzhu Yang, LuYao Li, Yuyuan Bai and Bin Zhao

Probiotics & Antimicro. Prot., 2026, 18, 822
DOI: 10.1007/s12602-025-10567-6

Antidiabetic activity of Solanum torvum fruit extract in streptozotocin-induced diabetic rats

Namani Satyanarayana, Suresh V. Chinni, Ramachawolran Gobinath, Paripelli Sunitha, Akula Uma Sankar and Bala Sundaram Muthuvenkatachalam

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.987552

Acute Pre- and Post-administration of Lactiplantibacillus plantarum 2034 and Its Secretory Metabolites Ameliorates Hyperglycaemia, Hyperlipidaemia, and Oxidative Stress in Diabetic Rats

Anmol Narang, Muzamil Rashid, Shubham Thakur, Subheet Kumar Jain, Amarjeet Kaur and Sukhraj Kaur

Probiotics & Antimicro. Prot., 2025, 17, 3999
DOI: 10.1007/s12602-024-10343-y

Vinegar-processed Schisandra chinensis polysaccharide ameliorates type 2 diabetes via modulation serum metabolic profiles, gut microbiota, and fecal SCFAs

Xingyu Guo, Yang Su, Yongqiang Du, Fan Zhang, Wenting Yu, Wenchen Ren, Shanshan Li, Haixue Kuang and Lun Wu

International Journal of Biological Macromolecules, 2025, 294, 139514
DOI: 10.1016/j.ijbiomac.2025.139514