Issue 18, 2016

Novel carbon-fiber microelectrode batch fabrication using a 3D-printed mold and polyimide resin

Abstract

Glass insulated carbon-fiber microelectrodes (CFMEs) are standard tools for the measurement of neurotransmitters. However, electrodes are fabricated individually and the glass can shatter, limiting application in higher order mammals. Here, we developed a novel microelectrode batch fabrication method using a 3D-printed mold and polyimide resin insulating agent. The 3D-printed mold is low cost, customizable to change the electrode shape, and allows 40 electrodes to be made simultaneously. The polyimide resin is biocompatible, quick to cure, and does not adhere to the plastic mold. The electrodes were tested for the response to dopamine with fast-scan cyclic voltammetry both in vitro and in vivo and performed similarly to traditional glass-insulated electrodes, but with lower background currents. Thus, polyimide-insulated electrodes can be mass-produced using a 3D-printed mold and are an attractive alternative for making cheap, biocompatible microelectrodes.

Graphical abstract: Novel carbon-fiber microelectrode batch fabrication using a 3D-printed mold and polyimide resin

Supplementary files

Article information

Article type
Communication
Submitted
29 มิ.ย. 2559
Accepted
10 ส.ค. 2559
First published
18 ส.ค. 2559

Analyst, 2016,141, 5256-5260

Novel carbon-fiber microelectrode batch fabrication using a 3D-printed mold and polyimide resin

E. Trikantzopoulos, C. Yang, M. Ganesana, Y. Wang and B. J. Venton, Analyst, 2016, 141, 5256 DOI: 10.1039/C6AN01469K

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