Issue 14, 2023

Supramolecular coordination complexes (SCCs) with aggregation-induced emission for in vitro photodynamic therapy

Abstract

Photodynamic therapy (PDT) has attracted a great deal of attention in the field of cancer treatment due to its non-invasive nature, high repeatability and minimal side effects. Due to the dual effect of organic small molecule donors and platinum receptors, supramolecular coordination complexes (SCCs) exhibit stronger reactive oxygen species (ROS) production capacity and have become a promising class of photosensitizers (PSs). Herein, we report a rhomboid SCC MD-CN based on the D–A structure with aggregation-induced emission (AIE). The results show that the as-prepared nanoparticles (NPs) had excellent photosensitization efficiency and good biocompatibility. Most importantly, they exhibited potential killing effects on cancer cells in vitro under light irradiation.

Graphical abstract: Supramolecular coordination complexes (SCCs) with aggregation-induced emission for in vitro photodynamic therapy

Supplementary files

Article information

Article type
Communication
Submitted
30 พ.ย. 2565
Accepted
16 มี.ค. 2566
First published
24 มี.ค. 2566

Dalton Trans., 2023,52, 4296-4302

Supramolecular coordination complexes (SCCs) with aggregation-induced emission for in vitro photodynamic therapy

H. Jia, T. Shi, T. He, Y. Li and S. Yin, Dalton Trans., 2023, 52, 4296 DOI: 10.1039/D2DT03855B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements