Issue 88, 2021

Co(iii)-catalysed regioselective linear C(8)–H olefination of isoquinolone with terminal aromatic and aliphatic alkynes

Abstract

A regioselective C8 linear olefination of isoquinoline-1H-2-one with terminal (aromatic and aliphatic) alkynes is reported under Co(III) catalysis. This is an exclusive report on the C8 functionalization of isoquinolone using non-noble transition metal complexes. Experimental and computational mechanistic studies have also been performed to depict the reaction pathway.

Graphical abstract: Co(iii)-catalysed regioselective linear C(8)–H olefination of isoquinolone with terminal aromatic and aliphatic alkynes

Supplementary files

Article information

Article type
Communication
Submitted
17 ส.ค. 2564
Accepted
29 ก.ย. 2564
First published
30 ก.ย. 2564

Chem. Commun., 2021,57, 11613-11616

Co(III)-catalysed regioselective linear C(8)–H olefination of isoquinolone with terminal aromatic and aliphatic alkynes

D. Chandra, N. Kumar, Sumit, D. Parmar, P. Gupta and U. Sharma, Chem. Commun., 2021, 57, 11613 DOI: 10.1039/D1CC04541E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements