Volume 219, 2019

Charge-tuning of glycosaminoglycan-based hydrogels to program cytokine sequestration

Abstract

Glycosaminoglycan (GAG)-based biohybrid hydrogels of varied GAG content and GAG sulfation pattern were prepared and applied to sequester cytokines. The binding of strongly acidic and basic cytokines correlated with the integral space charge density of the hydrogel, while the binding of weakly charged cytokines was governed by the GAG sulfation pattern.

Graphical abstract: Charge-tuning of glycosaminoglycan-based hydrogels to program cytokine sequestration

Associated articles

Article information

Article type
Paper
Submitted
11 ก.พ. 2562
Accepted
22 ก.พ. 2562
First published
22 ก.พ. 2562

Faraday Discuss., 2019,219, 244-251

Charge-tuning of glycosaminoglycan-based hydrogels to program cytokine sequestration

U. Freudenberg, P. Atallah, Y. D. P. Limasale and C. Werner, Faraday Discuss., 2019, 219, 244 DOI: 10.1039/C9FD00016J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements