Issue 35, 2016

Facile, tunable, and SERS-enhanced HEPES gold nanostars

Abstract

Gold nanoparticles have shown promise as effective tools in biomedicine for drug delivery, imaging, and photo thermal therapy. We present the preparation of gold nanostars (AuNSs) through a two-step approach utilizing a common Good's buffer, HEPES, as a weak reducing agent. AuNSs with tunable branch-lengths up to 30 nm in length were produced in a two-step synthesis. We have investigated the effect of the ionic strength on the AuNS growth and branch length. AuNSs were found to be near-infrared responsive and provide an augmented SERS signal, with an enhancement factor, defined as the magnitude of SERS signal amplification, of approximately 107. The unique branched morphology of the AuNSs confers optical properties advantageous for in vivo biomedical applications.

Graphical abstract: Facile, tunable, and SERS-enhanced HEPES gold nanostars

Supplementary files

Article information

Article type
Paper
Submitted
07 ม.ค. 2559
Accepted
09 มี.ค. 2559
First published
16 มี.ค. 2559

RSC Adv., 2016,6, 29669-29673

Facile, tunable, and SERS-enhanced HEPES gold nanostars

S. Saverot, X. Geng, W. Leng, P. J. Vikesland, T. Z. Grove and L. R. Bickford, RSC Adv., 2016, 6, 29669 DOI: 10.1039/C6RA00450D

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