Issue 20, 2016

PIDA–I2 mediated direct vicinal difunctionalization of olefins: iodoazidation, iodoetherification and iodoacyloxylation

Abstract

Iodinium cation (I+ or IOAc) was produced from the combination of phenyliodine diacetate (PIDA) and iodine. I+ facilitated the direct vicinal difunctionalization of olefins to α-azido, α-trideuteriomethoxy, α-2,2,2-trifluoroethoxy and α-acyloxy alkyl iodides via cation–π interaction at room temperature and under transition-metal free conditions.

Graphical abstract: PIDA–I2 mediated direct vicinal difunctionalization of olefins: iodoazidation, iodoetherification and iodoacyloxylation

Supplementary files

Article information

Article type
Paper
Submitted
10 มี.ค. 2559
Accepted
15 เม.ย. 2559
First published
15 เม.ย. 2559

Org. Biomol. Chem., 2016,14, 4654-4663

PIDA–I2 mediated direct vicinal difunctionalization of olefins: iodoazidation, iodoetherification and iodoacyloxylation

T. K. Achar, S. Maiti and P. Mal, Org. Biomol. Chem., 2016, 14, 4654 DOI: 10.1039/C6OB00532B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements