Pd-catalyzed selective tetrafunctionalization of diiodo-o-carboranes

Abstract

A palladium-catalyzed highly selective tetrafunctionalization of 3,6-I₂-o-carborane and 4,7-I₂-o-carborane has been developed, leading to the preparation of 3,6-dialkenyl-4,11-R₂-o-carboranes and 4,7-dialkenyl-5,11-R₂-o-carboranes (R = alkyl, allyl and aryl) in moderate to excellent yields. This represents a new strategy for selective synthesis of polyfunctionalized o-carborane derivatives via a one-pot process.