Themed collection Catalysis & biocatalysis in OBC

Organocatalytic methods and light-mediated methods have proved to be effective in chemical synthetic science. This paper compares them with the more established metal-catalyzed methods for the synthesis of a pharmaceutical core: coumarin.

Catalysis offers a straightforward route to prepare various value-added molecules starting from readily available raw materials.

The synthesis of nitrogen-containing heterocycles from β-aminovinyl esters(ketones) was reviewed according to the classification of the final heterocycle synthesis.

This review summarizes the recent advances in deoxygenation reactions of S–O, N–O and C–O bonds catalyzed by dioxomolybdenum(VI) complexes.

A comprehensive discussion on the organocatalytic applications of cyclopropene-based small molecules such as cyclopropenium salts, cyclopropenimines, cyclopropenylidenes, and cyclopropenones in organic transformations is reported.

This review highlights the applications of dirhodium(II,II) paddlewheel complexes with a heteroleptic scaffold.

Recent achievements in rhodium-catalyzed arylations through C(sp²)–H bond activation were summarized.

Heteroatoms (O and N) on the phthalazinones are exploited for diverse functionalization with high regioselectivity by the intervention of transition-metal catalysts like Rh, Ru, Pd, & Ir and, thus augmenting its value.

This review summarizes the most recent organometallic, photochemical and electrochemical methods for the synthesis of perfluoroalkylated aromatic scaffolds, a family of compounds that is omnipresent in modern commercial and research applications.

Rapid environmental changes triggered by the increase in the concentration of heat-absorbing gases such as CO₂ in the atmosphere have become a major cause of concern.

The review describes the syntheses and inhibition properties of pyrrolidine, piperidine, azepane, pyrrolizidine and indolizidine iminosugars, as well as iminosugar nucleotides and iminodi- and -oligosaccharides.

Thioxanthone is a powerful photocatalyst. In this review, its photophysical properties and its applications in photopolymerisation and in organic synthesis are highlighted.

This review features the recent advancement made in phosphorus-containing POPs, highlighting different synthetic techniques for their preparation and application in organic synthesis.

In this review article, recent advances in nickel-catalyzed hydrogen auto-transfer (HA) and acceptorless dehydrogenative coupling (ADC) reactions for the construction of C–C and C–N bonds have been discussed.

This mini-review aims to cover the Cu-catalyzed aerobic benzylic and α-carbonyl C_sp³–H oxidations and that of the carbon next to an amine group in the past five years.

Here…comes the fun…Combination of metals and organic photocatalysts allows the practical invention of new methodologies!

α,β-Unsaturated acyl ammonium species are versatile intermediates that have been applied in a variety of transformations including Michael additions, domino reactions and cycloadditions.

Aldehyde deformylation is one of the useful reactions in biology and organic syntheses and this review provides mechanistic insights into the same.

The review highlighted diverse annulations, including nitrogen, oxygen, sulfur heterocycles and carbocylizations via Rh(III)/Ir(III)-catalyzed C–H functionalization/annulation with various arene and carbene precursors.

Chiral β-nitroalcohols are versatile synthetic intermediates for several pharmaceuticals, and bioactive molecules. This review describes the importance and various biocatalytic approaches for their enantio and diastereoselective synthesis.

1,3-Dicyano-2,4,5,6-tetrakis(diphenylamino)-benzene has emerged as a powerful and attractive metal-free organophotocatalyst for organic transformation and is expected to contribute to a great extent toward the advancement and development of synthetic methodologies.

We review hybrid systems of abiotic catalysis and enzymatic catalysis, which function in living cells. This research direction will stimulate multidisciplinary fields, including complex molecule synthesis, energy production, and life science.

This review highlights recent advances in the synthesis and application of ferrocene-containing chiral ligands and organocatalysts in asymmetric catalysis.

An overview of transition metal catalyzed glycosylation reactions is presented and the main trends in reactivity are discussed.

The mild generation of nitrogen-centred radicals from N–F reagents using copper-based catalysts has become a convenient synthetic tool.

This review summarizes the advances in catalytic enantioselective reactions using CO₂ as a C1 synthon, introduces strategies and discusses advantages and limitations, highlights the application, and outlines the synthetic opportunities.

Carbohalofunctionalization of C–C multiple bonds via atom transfer radical processes constitutes an efficient method for the construction of halogenated building blocks with complete atom economy. This review summarizes the recent advancements.

Recent examples of organic synthesis of fine chemicals and pharmaceuticals in confined spaces of MOFs are highlighted and compared with silica-based ordered porous solids, such as zeolites or mesoporous (organo)silica.

Molecular crowding promotes RNA folding and catalysis and could have played vital roles in the evolution of primordial ribozymes and protocells.

Multicomponent reactions have demonstrated a remarkable impact on the synthesis of complex compounds, with high atom economy. In this review, the last decade contributions to enantioselective MCRs by focusing on catalytic approaches are discussed.

Direct carbonylation of the C–H bond is a great tool for installing a carbonyl group in a wide variety of substrates.

Chiral disulfonimides are a powerful class of organocatalysts that are amenable to an impressive scope of reaction types. This review provides a complete analysis of their synthesis, successful applications, mechanistic insights, and unmet challenges.

This review documents the potential of enantioselective gold catalysis for the functionalization of indoles.

This review describes the recent applications of thiourea-based organocatalysts in asymmetric multicomponent reactions.

Stereoselective copper-catalyzed conjugate additions of organometallic reagents serve as a versatile tool in the total syntheses of diverse natural compounds and pharmaceutical agents.

Catalytic decarboxylative reactions are attractive as biomimetic and environmentally friendly reaction processes. This review summarizes recent results for organocatalytic enantioselective decarboxylative reactions from October 2013 to December 2019.

In this review, the progress of tandem transformation of nitro, nitrile and azide functionalities is summarised to develop new C–C and C–N bonds as well as multi-component reactions using alcohols.

This review highlights the different enantioselective catalyst-controlled cascades creating multiple alcohol functions and ensuring through subsequent simple derivatization, the rapid preparation of extended 1,3-polyols.

In this mini-review, we attempt to highlight gaps in existing techniques for sp³ C–H activation adjacent to heterocycles.

A variety of catalytic asymmetric reactions have been realized during the past decade through the combined action of palladium and chiral phosphoric acids (CPAs). This review surveys key examples and examines the underlying mechanisms of stereoinduction.

Ready availability, low cost and low toxicity of cobalt salts have redirected the attention of researchers away from noble metals, such as Pd, Rh, and Ir, towards Co in the field of C–H functionalisation.

The recent advancements of modified TiO₂ materials as photocatalysts for organic synthesis are summarized.

The recent developments in the asymmetric functionalization of heterocycles via the catalytic enantioselective cross dehydrogenative coupling reactions of heterocyclic sp³ C–H bonds are highlighted in this review.

This review summarizes the beginning, progress, and prospects of non-canonical DNA-based hybrid catalysts focusing on G-quadruplexes as versatile scaffolds for catalysis.

Asymmetric visible-light photocatalysis has recently drawn considerable attention of the scientific community owing to its unique activation modes and significance for the enantioselective green synthesis.

Review covering the synthesis of 5- and 6-membered as well as condensed heteroarenes, focussing on the combinations in cooperative catalytic systems in strategies used to achieve selectivity and also highlights the mode of action for the cooperative catalysis leading to the synthesis of commercially and biologically relevant heteroarenes.

This review describes the advances in the design and application of novel artificial metalloenzymes in C–H activation reactions.

The achievements of chiral metal complex-catalyzed enantiodivergent reactions during the period from 2008 to present were updated.

This short review presents the current main chemical warfare agents and their most relevant simulants, and the recent catalytic and selective methods for their soft neutralization, potentially usable in the future as an alternative to “heavy” methods for decontamination.

This review covers the methods for the preparation of chiral palladium(II) pincer complexes and their applications in asymmetric catalysis.

A review of metal–guanidine complexes, which are selective and powerful catalysts for organic transformations, asymmetric synthesis, and polymerisation.

This review highlights the recent advances in photocatalytic manipulations of Rose Bengal in organic synthesis.

Review of recent advances in asymmetric catalytic cycloaddition reactions of silyl-protected enoldiazo compounds.

Dual mechanisms for H-bond mediated ring-opening polymerization allow for precise control, high activity and new applications.

We present recent advances in prominent organotransition metal-catalysed reactions in which Lewis acid cocatalysts are employed to increase catalyst activity or selectivity. The roles of Lewis acids are discussed.

The present review summarizes the recent development of N-alkylation of amides with alcohols according to the classification of catalysts.

The role of silver salts in Pd-catalysed C–C bond forming transformations.

Factors that affect the efficiency of amine transaminase catalyzed reactions using isopropylamine as an amine donor.

This review updates advances of direct C(sp²)–H nitration for the synthesis of nitroaromatic compounds and the mechanisms during the past decade.

Chemistry of diazo compounds is dominated by transition metal catalysis but recently, photoinitiated reactions of diazo compounds have attracted a lot of attention. This mini-review describes recent discoveries on the reactivity of diazo compounds under light irradiation.

This Review article provides a summary and critical metrics-based analysis of recently developed catalytic Mitsunobu reactions.

This review focuses on indium(III) as a π-acid for the activation of C–C unsaturated systems (alkynes, alkenes, and allenes) in organic synthesis.

The trans-chelating bis(oxazoline) ligand (R,R)-4,6-dibenzofurandiyl-2,2′-bis(4-phenyloxazoline) [(R,R)-DBFOX/Ph] coordinates metal ions to give C₂-symmetric complexes which effectively catalyze a variety of asymmetric reactions.

The implementation of chiral iodine catalysis has tremendously been developed in the field of asymmetric synthesis over the past decade.

This review describes the synthetic methods for the preparation of chiral spirocyclic phosphoric acids (SPAs), and their dynamically developing application for catalytic enantioselective transformations.

The use of halo-substituted ArSO₂R as an aryl source in metal-catalyzed C–C bond formation reactions presents several advantages, as the reaction often proceeds without cleavage of the C–halo bonds.

The development of chiral proton-transfer shuttles provides a totally new enantiocontrol strategy for transition metal-catalyzed asymmetric carbene insertion reactions.

This review article gives an overview of the recent development of iodine mediated electrochemical oxidative coupling reactions.

Recent advances in catalytic enantioselective enamine protonation for the synthesis of optically active carbonyl compounds are summarized in this review.

Terpenoid structural diversity is enhanced by multiproduct enzymes. Biosynthesis can be altered by switch in substrates, cofactors and pH.