Rhodanine-pyridinium derivatives as a new category of cholinesterase inhibitors: Design, synthesis, in vitro and in silico enzymatic evaluations

Milad Noori, Somaye Karimian, Navid Dastyafteh, Seyedeh Niloufar Ghafouri, Maryam Mohammadi-Khanaposhtani, Sajedeh Safapoor, Minoo Khalili Ghomi, Hossein Rastegar, Saeedeh Saeedi, Bagher Larijani, Mohammad Mahdavi, Aydın Aktaş, Parham Taslimi and İlhami Gülçin

International Journal of Biological Macromolecules, 2025, 320, 145731
DOI: 10.1016/j.ijbiomac.2025.145731

1H-benzo[f]chromene-2-carboxylate derivatives: synthesis, computational investigations (docking, MD, and DFT), and in vitro biological evaluation as tyrosinase inhibitors

Somaye Karimian, Niloofar Nikeghbali, Asma Nahaei, Maryam Kabiri, Alireza Poustforoosh, Amirhossein Sakhteman and Mehdi Khoshneviszadeh

Results in Chemistry, 2026, 21, 103047
DOI: 10.1016/j.rechem.2026.103047

Design of novel benzimidazole-propane hydrazide derivatives as α-glucosidase and α-amylase inhibitors: in vitro and in silico studies

Shiva Mohammadizadeh, Somaye Karimian, Navid Dastyafteh, Milad Noori, Fatemeh Doraghi, Maryam Mohammadi-Khanaposhtani, Bagher Larijani, Mohammad Mahdavi, Nastaran Sadeghian, Aydın Aktaş, Parham Taslimi and İlhami Gulçin

Med Chem Res, 2025, 34, 205
DOI: 10.1007/s00044-024-03328-7

1,3,5-Triazine: A Promising Molecular Scaffold for Novel Agents for the Treatment of Alzheimer’s Disease

Carlos F. M. Silva, Ana P. D. de M. S. Guerrinha, Sofia Carvalho, Diana C. G. A. Pinto and Artur M. S. Silva

IJMS, 2025, 26, 882
DOI: 10.3390/ijms26030882

Design, Synthesis, Molecular Docking Studies, Antioxidant Effects, and Enzyme Inhibition of 3‐Aryl‐4‐Hydroxy‐6‐Methyl‐2H‐Pyran‐2‐One Derivatives as Mushroom Tyrosinase Inhibitors

Somaye Karimian, Donya Mazheri, Somaye Pirhadi, Maryam Shahriyari, Mohammadbagher Bahmani, Razieyeh Sabet and Mehdi Khoshneviszadeh

ChemistrySelect, 2025, 10
DOI: 10.1002/slct.202504746

New benzimidazole–indole–amide derivatives as potent α‐glucosidase and acetylcholinesterase inhibitors

Narges Naimi, Somaye Karimian, Navid Dastyafteh, Mild Noori, Maryam Mohammadi‐Khanaposhtani, Armin Dadgar, Bagher Larijani, Vahid Lotfi, İlhami Çelik, Aydın Aktaş, Nastaran Sadeghian, Parham Taslimi and Mohammad Mahdavi

Archiv der Pharmazie, 2025, 358
DOI: 10.1002/ardp.202400354

Introduction of new quinolone-2-thio-acetamide-propane hydrazide-benzimidazole derivatives as new α-glucosidase and α-amylase inhibitors

Parisa Nikfar, Somaye Karimian, Sajedeh Safapoor, Milad Noori, Navid Dastyafteh, Seyedeh Niloufar Ghafouri, Maryam Mohammadi-Khanaposhtani, Bagher Larijani, Parham Taslimi and Mohammad Mahdavi

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-16661-7

Design, synthesis and anticholinesterase activity of coumarin-1,3,5-triazine derivatives

Xiao-Qing Zhang, Liu-Qing Shi, Zhao-Yuan Zhang, Shu-Tong Han, Zhi-Hai Zhao, Kun-Xiao Zhang and Da-Hua Shi

Journal of Molecular Structure, 2025, 1339, 142439
DOI: 10.1016/j.molstruc.2025.142439

Design, Synthesis and Anticholinesterase Activity of Coumarin‐1,3,5‐triazine Derivatives

Xiao‐Qing Zhang, Jing Wang, Jing‐Pei Zou, Yang Cao, Xu‐Hui Xu, Bo Ding, Wei‐Wei Liu, Shao‐Jie Ma and Da‐Hua Shi

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202303428

Molecular modeling and biological investigation of novel s-triazine linked benzothiazole and coumarin hybrids as antimicrobial and antimycobacterial agents

Ajayrajsinh R. Zala, Dinesh Kumar, Uvais Razakhan, Dhanji P. Rajani, Iqrar Ahmad, Harun Patel and Premlata Kumari

Journal of Biomolecular Structure and Dynamics, 2024, 42, 3814
DOI: 10.1080/07391102.2023.2216293

A comprehensive review of multi-target directed ligands in the treatment of Alzheimer’s disease

Chandni Pathak and Uma D. Kabra

Bioorganic Chemistry, 2024, 144, 107152
DOI: 10.1016/j.bioorg.2024.107152

Design, Synthesis, and Biological Activity of Novel 1,3,5-Triazine–1,2,4-Triazine Hybrids as Cholinesterase Inhibitors

Chang-E. Dong, Rui Li, Zai-Xiu Pan, He Li, Jing-Jing Qian, Wei-Wei Liu, Zhi-Ling Cao and Da-Hua Shi

Russ J Org Chem, 2023, 59, 1610
DOI: 10.1134/S1070428023090191