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DOI: 10.1039/D5CC00090D

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DOI: 10.1158/1535-7163.MCT-23-0393

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DOI: 10.1186/s13048-024-01523-z

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DOI: 10.1002/anie.202402267

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Antibodies, 2023, 12, 72
DOI: 10.3390/antib12040072

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DOI: 10.1021/acs.chemrev.2c00915

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Drug Metabolism and Disposition, 2023, 51, 1324
DOI: 10.1124/dmd.123.001313

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DOI: 10.1016/j.phrs.2024.107160

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DOI: 10.1002/ange.202402267

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DOI: 10.3390/ijms252413356

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BMC Cancer, 2024, 24
DOI: 10.1186/s12885-024-12652-5

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DOI: 10.1038/s44303-024-00027-1

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European Journal of Medicinal Chemistry, 2023, 257, 115489
DOI: 10.1016/j.ejmech.2023.115489

Tumor-targeted and stimulus-responsive polymeric prodrug nanoparticles to enhance the anticancer therapeutic efficacy of doxorubicin

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DOI: 10.1016/j.jconrel.2024.03.046

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Top Curr Chem (Z), 2025, 383
DOI: 10.1007/s41061-025-00497-w

Synthesis of α/β-Aromatic Peroxy Thiols Mediated by Iodine Source

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DOI: 10.1021/acs.joc.3c02518