Conjugation of 4-(dimethylamino)pyridine to primary amines in aqueous buffer solutions using an N-hydroxysuccinimide ester reagent

Saki Horie, Hikaru Fujita, Rina Yamashita and Munetaka Kunishima

Tetrahedron Letters, 2021, 81, 153343
DOI: 10.1016/j.tetlet.2021.153343

Live-cell epigenome manipulation by synthetic histone acetylation catalyst system

Yusuke Fujiwara, Yuki Yamanashi, Akiko Fujimura, Yuko Sato, Tomoya Kujirai, Hitoshi Kurumizaka, Hiroshi Kimura, Kenzo Yamatsugu, Shigehiro A. Kawashima and Motomu Kanai

Proc. Natl. Acad. Sci. U.S.A., 2021, 118
DOI: 10.1073/pnas.2019554118

Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry

Rambabu N. Reddi, Adi Rogel, Efrat Resnick, Ronen Gabizon, Pragati Kishore Prasad, Neta Gurwicz, Haim Barr, Ziv Shulman and Nir London

J. Am. Chem. Soc., 2021, 143, 20095
DOI: 10.1021/jacs.1c06167

Catalysis medicine: Participating in the chemical networks of living organisms through catalysts

Motomu Kanai and Yuma Takeuchi

Tetrahedron, 2023, 131, 133227
DOI: 10.1016/j.tet.2022.133227

Designer Catalyst-Enabled Regiodivergent Histone Acetylation

Tamiko Nozaki, Mayu Onoda, Misuzu Habazaki, Yuma Takeuchi, Hisashi Ishida, Yuko Sato, Tomoya Kujirai, Kayo Hanada, Kenzo Yamatsugu, Hitoshi Kurumizaka, Hiroshi Kimura, Hidetoshi Kono, Shigehiro A. Kawashima and Motomu Kanai

J. Am. Chem. Soc., 2025, 147, 13732
DOI: 10.1021/jacs.5c01699

Advances and Opportunities in Epigenetic Chemical Biology

Jenna N. Beyer, Nicole R. Raniszewski and George M. Burslem

ChemBioChem, 2021, 22, 17
DOI: 10.1002/cbic.202000459

Chemical Catalysis Intervening to Histone Epigenetics

Tamiko Nozaki and Motomu Kanai

Acc. Chem. Res., 2021, 54, 2313
DOI: 10.1021/acs.accounts.1c00144

Live-Cell Protein Modification by Boronate-Assisted Hydroxamic Acid Catalysis

Christopher Adamson, Hidetoshi Kajino, Shigehiro A. Kawashima, Kenzo Yamatsugu and Motomu Kanai

J. Am. Chem. Soc., 2021, 143, 14976
DOI: 10.1021/jacs.1c07060

A chemical catalyst enabling histone acylation with endogenous acyl-CoA

Misuzu Habazaki, Shinsuke Mizumoto, Hidetoshi Kajino, Tomoya Kujirai, Hitoshi Kurumizaka, Shigehiro A. Kawashima, Kenzo Yamatsugu and Motomu Kanai

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-41426-z

Designer Adaptor Proteins for Functional Conversion of Peptides to Small-Molecule Ligands toward In-Cell Catalytic Protein Modification

Akiko Fujimura, Hisashi Ishida, Tamiko Nozaki, Shuhei Terada, Yuto Azumaya, Tadashi Ishiguro, Yugo R. Kamimura, Tomoya Kujirai, Hitoshi Kurumizaka, Hidetoshi Kono, Kenzo Yamatsugu, Shigehiro A. Kawashima and Motomu Kanai

ACS Cent. Sci., 2023, 9, 2115
DOI: 10.1021/acscentsci.3c00930