The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells

Jong Hyun Lee, Chakrabhavi Dhananjaya Mohan, Salundi Basappa, Shobith Rangappa, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Alan Prem Kumar, Gautam Sethi, Kwang Seok Ahn and Kanchugarakoppal S Rangappa

Biomolecules, 2019, 9, 875
DOI: 10.3390/biom9120875

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

C. P. Baburajeev, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Daniel J. Mason, Julian E. Fuchs, Andreas Bender, Uri Barash, Israel Vlodavsky, Basappa and Kanchugarakoppal S. Rangappa

BMC Cancer, 2017, 17
DOI: 10.1186/s12885-017-3214-8

Paradoxical functions of long noncoding RNAs in modulating STAT3 signaling pathway in hepatocellular carcinoma

Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, S. Chandra Nayak, Gautam Sethi and Kanchugarakoppal S. Rangappa

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2021, 1876, 188574
DOI: 10.1016/j.bbcan.2021.188574

Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma

Jong Hyun Lee, Shobith Rangappa, Chakrabhavi Dhananjaya Mohan, Basappa, Gautam Sethi, Zhi-Xiu Lin, Kanchugarakoppal S. Rangappa and Kwang Seok Ahn

Biomolecules, 2019, 9, 550
DOI: 10.3390/biom9100550

Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response

Milad Ashrafizadeh, Chakrabhavi D. Mohan, Shobith Rangappa, Ali Zarrabi, Kiavash Hushmandi, Alan Prem Kumar, Gautam Sethi and Kanchugarakoppal S. Rangappa

Medicinal Research Reviews, 2023, 43, 1263
DOI: 10.1002/med.21950

Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma

Jong Hyun Lee, Chakrabhavi Dhananjaya Mohan, Amudha Deivasigamani, Young Yun Jung, Shobith Rangappa, Salundi Basappa, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Manoj Garg, Zhi-Xiu Lin, Kanchugarakoppal S. Rangappa, Gautam Sethi, Kam Man Hui and Kwang Seok Ahn

Journal of Advanced Research, 2020, 26, 83
DOI: 10.1016/j.jare.2020.07.004

Green Synthesis of Silver Nanoparticles by Cytobacillus firmus Isolated from the Stem Bark of Terminalia arjuna and Their Antimicrobial Activity

Sujesh Sudarsan, Madan Kumar Shankar, Anil Kumar Belagal Motatis, Sushmitha Shankar, Darshan Krishnappa, Chakrabhavi Dhananjaya Mohan, Kanchugarakoppal S. Rangappa, Vijai Kumar Gupta and Chandra Nayaka Siddaiah

Biomolecules, 2021, 11, 259
DOI: 10.3390/biom11020259

Genistein: a promising modulator of apoptosis and survival signaling in cancer

Hemant Joshi, Dhruv Sanjay Gupta, Nosheen Kamruddin Abjani, Ginpreet Kaur, Chakrabhavi Dhananjaya Mohan, Jagjit Kaur, Diwakar Aggarwal, Isha Rani, Seema Ramniwas, Hadi Sajid Abdulabbas, Madhu Gupta and Hardeep Singh Tuli

Naunyn-Schmiedeberg's Arch Pharmacol, 2023, 396, 2893
DOI: 10.1007/s00210-023-02550-1

DESIGN, PREPARATION, AND IN SILICO STUDY OF NOVEL CURCUMIN-BIPHENYL CARBONITRILE CONJUGATE AS NOVEL ANTICANCER DRUG MOLECULES

GEETA KRISHNAMURTHY, LAIRIKYENGBAM DEEPTI ROY, JYOTSNA KUMAR, POOJA GOUR, SHIVANJALI ESTHER ARLAND, NAVEED REHMAN, SRINIVASA GR and SRINIVAS MT

Int J App Pharm, 2023, 143
DOI: 10.22159/ijap.2023v15i4.45811

Synthesis, characterization and cytotoxicity studies of 1,2,3-triazoles and 1,2,4-triazolo [1,5-a] pyrimidines in human breast cancer cells

Maryam Gilandoust, Kachigere B. Harsha, Chakrabhavi Dhananjaya Mohan, Ainiah Rushdiana Raquib, Shobith Rangappa, Vijay Pandey, Peter E. Lobie, Basappa and Kanchugarakoppal S. Rangappa

Bioorganic & Medicinal Chemistry Letters, 2018, 28, 2314
DOI: 10.1016/j.bmcl.2018.05.020

Synthesis, Cytotoxic and Heparanase Inhibition Studies of 5-oxo-1-arylpyrrolidine-3- carboxamides of Hydrazides and 4-amino-5-aryl-4H-1,2,4-triazole-3-thiol

Swetha Hari, Toreshettahally R. Swaroop, Habbanakuppe D. Preetham, Chakrabhavi D. Mohan, Umashakara Muddegowda, Salundi Basappa, Israel Vlodavsky, Gautam Sethi and Kanchugarakoppal S. Rangappa

COS, 2020, 17, 243
DOI: 10.2174/1570179417666200225123329

Carbazole Derivatives as STAT Inhibitors: An Overview

Anna Caruso, Alexia Barbarossa, Alessia Carocci, Giovanni Salzano, Maria Stefania Sinicropi and Carmela Saturnino

Applied Sciences, 2021, 11, 6192
DOI: 10.3390/app11136192

Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway

Jong Hyun Lee, Chakrabhavi Dhananjaya Mohan, Muthu K. Shanmugam, Shobith Rangappa, Gautam Sethi, Kodappully Sivaraman Siveen, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Salundi Basappa, Kanchugarakoppal S. Rangappa and Kwang Seok Ahn

Biochimie, 2020, 175, 58
DOI: 10.1016/j.biochi.2020.05.006

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

Anilkumar C. Nirvanappa, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Hanumappa Ananda, Alexey Yu Sukhorukov, Muthu K. Shanmugam, Mahalingam S. Sundaram, Siddaiah Chandra Nayaka, Kesturu S. Girish, Arunachalam Chinnathambi, M. E. Zayed, Sulaiman Ali Alharbi, Gautam Sethi, Basappa, Kanchugarakoppal S. Rangappa and Shrikant Anant

PLoS ONE, 2016, 11, e0163209
DOI: 10.1371/journal.pone.0163209

Omega-3 Polyunsaturated Fatty Acids Provoke Apoptosis in Hepatocellular Carcinoma through Knocking Down the STAT3 Activated Signaling Pathway: In Vivo and In Vitro Study

Noura M. Darwish, Mohamed M. A. Elshaer, Saeedah Musaed Almutairi, Tse-Wei Chen, Mohamed Othman Mohamed, Wael B. A. Ghaly and Rabab Ahmed Rasheed

Molecules, 2022, 27, 3032
DOI: 10.3390/molecules27093032

3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular Carcinoma

Chakrabhavi Dhananjaya Mohan, Min Hee Yang, Shobith Rangappa, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Tahani Awad Alahmadi, Amudha Deivasigamani, Kam Man Hui, Gautam Sethi, Kanchugarakoppal S. Rangappa and Kwang Seok Ahn

Biology, 2021, 11, 29
DOI: 10.3390/biology11010029

Novel 1,3,4-oxadiazole Targets STAT3 Signaling to Induce Antitumor Effect in Lung Cancer

Vikas H. Malojirao, Swamy S. Girimanchanaika, Muthu K. Shanmugam, Ankith Sherapura, Dukanya, Prashant K. Metri, Vellingiri Vigneshwaran, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Shobith Rangappa, Chakrabhavi Dhananjaya Mohan, Basappa, Bettadathunga T. Prabhakar and Kanchugarakoppal S. Rangappa

Biomedicines, 2020, 8, 368
DOI: 10.3390/biomedicines8090368

Pyrimidine-2,4-dione targets STAT3 signaling pathway to induce cytotoxicity in hepatocellular carcinoma cells

Ayyiliath M Sajith, Kereyagalahally H. Narasimhamurthy, Muthu K. Shanmugam, Shobith Rangappa, S. Chandra Nayak, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, K.R. Haridas, E.K. Reddy, B. Savitha, Chakrabhavi Dhananjaya Mohan and Kanchugarakoppal S. Rangappa

Bioorganic & Medicinal Chemistry Letters, 2021, 50, 128332
DOI: 10.1016/j.bmcl.2021.128332

Crocetin imparts antiproliferative activity via inhibiting STAT3 signaling in hepatocellular carcinoma

Chakrabhavi Dhananjaya Mohan, Chulwon Kim, Kodappully Sivaraman Siveen, Kanjoormana Aryan Manu, Shobith Rangappa, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Kanchugarakoppal S. Rangappa, Alan Prem Kumar and Kwang Seok Ahn

IUBMB Life, 2021, 73, 1348
DOI: 10.1002/iub.2555