Functional and Structural Properties of a Novel Protein and Virulence Factor (Protein sHIP) in Streptococcus pyogenes

Magdalena Wisniewska, Lotta Happonen, Fredrik Kahn, Markku Varjosalo, Lars Malmström, George Rosenberger, Christofer Karlsson, Giuseppe Cazzamali, Irina Pozdnyakova, Inga-Maria Frick, Lars Björck, Werner Streicher, Johan Malmström and Mats Wikström

Journal of Biological Chemistry, 2014, 289, 18175
DOI: 10.1074/jbc.M114.565978

Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS

Christofer A.Q. Karlsson, Sofia Järnum, Lena Winstedt, Christian Kjellman, Lars Björck, Adam Linder and Johan A. Malmström

Molecular & Cellular Proteomics, 2018, 17, 1097
DOI: 10.1074/mcp.RA117.000525

Application of targeted mass spectrometry in bottom-up proteomics for systems biology research

Nathan P. Manes and Aleksandra Nita-Lazar

Journal of Proteomics, 2018, 189, 75
DOI: 10.1016/j.jprot.2018.02.008

The intricate pathogenicity of Group A Streptococcus : A comprehensive update

Helena Bergsten and Victor Nizet

Virulence, 2024, 15
DOI: 10.1080/21505594.2024.2412745

Plasma Protein Layer Concealment Protects Streptococcus pyogenes From Innate Immune Attack

Hilger Jagau, Swathi Packirisamy, Kyle Brandon and Heiko Herwald

Front. Cell. Infect. Microbiol., 2021, 11
DOI: 10.3389/fcimb.2021.633394

Targeted mass spectrometry analysis of neutrophil-derived proteins released during sepsis progression

Erik Malmström, Alzbeta Davidova, Matthias Mörgelin, Adam Linder, Michael Larsen, Klaus Qvortrup, Pontus Nordenfelt, Oonagh Shannon, Olga Dzupova, Michal Holub, Johan Malmström and Heiko Herwald

Thromb Haemost, 2014, 112, 1230
DOI: 10.1160/th14-04-0312

Streptococcus pyogenes Escapes Killing from Extracellular Histones through Plasminogen Binding and Activation by Streptokinase

Ramona Nitzsche, Juliane Köhler, Bernd Kreikemeyer and Sonja Oehmcke-Hecht

J Innate Immun, 2016, 8, 589
DOI: 10.1159/000448039

Proteomic and Metaproteomic Approaches to Understand Host–Microbe Interactions

Amanda E. Starr, Shelley A. Deeke, Leyuan Li, Xu Zhang, Rachid Daoud, James Ryan, Zhibin Ning, Kai Cheng, Linh V. H. Nguyen, Elias Abou-Samra, Mathieu Lavallée-Adam and Daniel Figeys

Anal. Chem., 2018, 90, 86
DOI: 10.1021/acs.analchem.7b04340

A quantitative Streptococcus pyogenes–human protein–protein interaction map reveals localization of opsonizing antibodies

Lotta Happonen, Simon Hauri, Gabriel Svensson Birkedal, Christofer Karlsson, Therese de Neergaard, Hamed Khakzad, Pontus Nordenfelt, Mats Wikström, Magdalena Wisniewska, Lars Björck, Lars Malmström and Johan Malmström

Nat Commun, 2019, 10
DOI: 10.1038/s41467-019-10583-5

Computational Health Engineering Applied to Model Infectious Diseases and Antimicrobial Resistance Spread

Mónica Cartelle Gestal, Margaret R. Dedloff and Eva Torres-Sangiao

Applied Sciences, 2019, 9, 2486
DOI: 10.3390/app9122486

Proteomic characterization of the interactions between fish serum proteins and waterborne bacteria reveals the suppression of anti-oxidative defense as a serum-mediated antimicrobial mechanism

Miao Dong, Yimin Liang, Rajkumar Ramalingam, Sze Wing Tang, Wei Shen, Rui Ye, Singaram Gopalakrishnan, Doris Wai Ting Au and Yun Wah Lam

Fish & Shellfish Immunology, 2017, 62, 96
DOI: 10.1016/j.fsi.2017.01.013

Quantitative proteomic characterization of lung-MSC and bone marrow-MSC using DIA-mass spectrometry

Sara Rolandsson Enes, Emma Åhrman, Anitha Palani, Oskar Hallgren, Leif Bjermer, Anders Malmström, Stefan Scheding, Johan Malmström and Gunilla Westergren-Thorsson

Sci Rep, 2017, 7
DOI: 10.1038/s41598-017-09127-y

Differential compartmentalization of Streptococcus pyogenes virulence factors and host protein binding properties as a mechanism for host adaptation

Ola Kilsgård, Christofer Karlsson, Erik Malmström and Johan Malmström

International Journal of Medical Microbiology, 2016, 306, 504
DOI: 10.1016/j.ijmm.2016.06.007

Proteomic analysis at the sites of clinical infection with invasive Streptococcus pyogenes

Robert J. Edwards, Marta Pyzio, Magdalena Gierula, Claire E. Turner, Vahitha B. Abdul-Salam and Shiranee Sriskandan

Sci Rep, 2018, 8
DOI: 10.1038/s41598-018-24216-2

Rapid determination of quaternary protein structures in complex biological samples

Simon Hauri, Hamed Khakzad, Lotta Happonen, Johan Teleman, Johan Malmström and Lars Malmström

Nat Commun, 2019, 10
DOI: 10.1038/s41467-018-07986-1

Candida albicans Shaving to Profile Human Serum Proteins on Hyphal Surface

Elvira Marín, Claudia M. Parra-Giraldo, Carolina Hernández-Haro, María L. Hernáez, César Nombela, Lucía Monteoliva and Concha Gil

Front. Microbiol., 2015, 6
DOI: 10.3389/fmicb.2015.01343

Antibacterial Activity of Rainbow Trout Plasma: In Vitro Assays and Proteomic Analysis

Toita Mizaeva, Kalimat Alieva, Eldar Zulkarneev, Stanislav Kurpe, Kseniya Isakova, Svetlana Matrosova, Ekaterina Borvinskaya and Irina Sukhovskaya

Animals, 2023, 13, 3565
DOI: 10.3390/ani13223565

Complement Activation Occurs at the Surface of Platelets Activated by Streptococcal M1 Protein and This Results in Phagocytosis of Platelets

Frida Palm, Kristoffer Sjöholm, Johan Malmström and Oonagh Shannon

The Journal of Immunology, 2019, 202, 503
DOI: 10.4049/jimmunol.1800897

Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Hamed Khakzad, Lotta Happonen, Yasaman Karami, Sounak Chowdhury, Gizem Ertürk Bergdahl, Michael Nilges, Guy Tran Van Nhieu, Johan Malmström, Lars Malmström and Alexey Onufriev

PLoS Comput Biol, 2021, 17, e1008169
DOI: 10.1371/journal.pcbi.1008169

Bioinformatic Analysis of Dihomo-γ-linolenic Acid (DGLA) Targeting Virulence Factors in Bacteria Causing Infectious Diseases

Nawan Nawan, Septi Handayani and Agnes Immanuela Toemon

Iran J Med Microbiol, 2025, 19, 12
DOI: 10.30699/ijmm.19.1.12

The Transcriptional Regulator CpsY Is Important for Innate Immune Evasion in Streptococcus pyogenes

Luis A. Vega, Kayla M. Valdes, Ganesh S. Sundar, Ashton T. Belew, Emrul Islam, Jacob Berge, Patrick Curry, Steven Chen, Najib M. El-Sayed, Yoann Le Breton, Kevin S. McIver and Nancy E. Freitag

Infect Immun, 2017, 85
DOI: 10.1128/IAI.00925-16

Targeted Proteomics for Studying Pathogenic Bacteria

Sara Saleh, An Staes, Stijn Deborggraeve and Kris Gevaert

Proteomics, 2019, 19
DOI: 10.1002/pmic.201800435

Targeted Proteomics and Absolute Protein Quantification for the Construction of a Stoichiometric Host-Pathogen Surface Density Model

Kristoffer Sjöholm, Ola Kilsgård, Johan Teleman, Lotta Happonen, Lars Malmström and Johan Malmström

Molecular & Cellular Proteomics, 2017, 16, S29
DOI: 10.1074/mcp.M116.063966

Proteomic Approaches to Unravel Mechanisms of Antibiotic Resistance and Immune Evasion of Bacterial Pathogens

Eva Torres-Sangiao, Alexander Dyason Giddey, Cristina Leal Rodriguez, Zhiheng Tang, Xiaoyun Liu and Nelson C. Soares

Front. Med., 2022, 9
DOI: 10.3389/fmed.2022.850374

Molecular characterization of the interaction between human IgG and the M-related proteins from Streptococcus pyogenes

Emma-Jayne Proctor, Hannah R. Frost, Sandeep Satapathy, Gwenaëlle Botquin, Joanna Urbaniec, Jody Gorman, David M.P. De Oliveira, Jason McArthur, Mark R. Davies, Anne Botteaux, Pierre Smeesters and Martina Sanderson-Smith

Journal of Biological Chemistry, 2024, 300, 105623
DOI: 10.1016/j.jbc.2023.105623