Effect of lipid architecture on cubic phase susceptibility to crystallisation screens

Charlotte E. Conn, Connie Darmanin, Xavier Mulet, Adrian Hawley and Calum J. Drummond

Soft Matter, 2012, 8, 6884
DOI: 10.1039/c2sm25705j

Nanostructured bicontinuous cubic lipid self-assembly materials as matrices for protein encapsulation

Charlotte E. Conn and Calum J. Drummond

Soft Matter, 2013, 9, 3449
DOI: 10.1039/c3sm27743g

Nanostructure and cytotoxicity of self-assembled monoolein–capric acid lyotropic liquid crystalline nanoparticles

Nhiem Tran, Xavier Mulet, Adrian M. Hawley, Tracey M. Hinton, Stephen T. Mudie, Benjamin W. Muir, Emma C. Giakoumatos, Lynne J. Waddington, Nigel M. Kirby and Calum J. Drummond

RSC Adv., 2015, 5, 26785
DOI: 10.1039/C5RA02604K

An X-ray transparent microfluidic platform for screening of the phase behavior of lipidic mesophases

Daria S. Khvostichenko, Elena Kondrashkina, Sarah L. Perry, Ashtamurthy S. Pawate, Keith Brister and Paul J. A. Kenis

Analyst, 2013, 138, 5384
DOI: 10.1039/c3an01174g

The nanoscience behind the art of in-meso crystallization of membrane proteins

Alexandru Zabara, Thomas G. Meikle, Janet Newman, Thomas S. Peat, Charlotte E. Conn and Calum J. Drummond

Nanoscale, 2017, 9, 754
DOI: 10.1039/C6NR07634C

Lyotropic liquid crystal engineering moving beyond binary compositional space – ordered nanostructured amphiphile self-assembly materials by design

Leonie van ‘t Hag, Sally L. Gras, Charlotte E. Conn and Calum J. Drummond

Chem. Soc. Rev., 2017, 46, 2705
DOI: 10.1039/C6CS00663A

Protein-Eye View of the in Meso Crystallization Mechanism

Leonie van ‘t Hag, Liliana de Campo, Nhiem Tran, Anna Sokolova, Raphael Trenker, Matthew E. Call, Melissa J. Call, Christopher J. Garvey, Anna E. Leung, Tamim A. Darwish, Anwen Krause-Heuer, Robert Knott, Thomas G. Meikle, Calum J. Drummond, Raffaele Mezzenga and Charlotte E. Conn

Langmuir, 2019
DOI: 10.1021/acs.langmuir.9b00647

Using a selective cadmium-binding peplipid to create responsive liquid crystalline nanomaterials

Qingtao Liu, Jinfeng Wang, Yao-Da Dong and Ben J. Boyd

Journal of Colloid and Interface Science, 2015, 449, 122
DOI: 10.1016/j.jcis.2014.11.063

Uptake of the butyrate receptors, GPR41 and GPR43, in lipidic bicontinuous cubic phases suitable for in meso crystallization

Yi-Lynn Liang, Charlotte E. Conn, Calum J. Drummond and Connie Darmanin

Journal of Colloid and Interface Science, 2015, 441, 78
DOI: 10.1016/j.jcis.2014.11.006

A systematic study of the effect of lipid architecture on cytotoxicity and cellular uptake of cationic cubosomes

S. Pushpa Ragini, Brendan P. Dyett, Sampa Sarkar, Jiali Zhai, Jacinta F. White, Rajkumar Banerjee, Calum J. Drummond and Charlotte E. Conn

Journal of Colloid and Interface Science, 2024, 663, 82
DOI: 10.1016/j.jcis.2024.02.099

Effect of cinnamic acid on phase transition and pH-dependent release property of monoolein cubic phase

Hong Zhang and Jin-Chul Kim

Journal of Industrial and Engineering Chemistry, 2015, 32, 319
DOI: 10.1016/j.jiec.2015.09.014

Electrochemical and biological characterization of lyotropic liquid crystalline phases – retardation of drug release from hexagonal mesophases

Ewa Nazaruk, Agnieszka Majkowska-Pilip, Marlena Godlewska, Mirosław Salamończyk and Damian Gawel

Journal of Electroanalytical Chemistry, 2018, 813, 208
DOI: 10.1016/j.jelechem.2018.01.029

Multiple Routes to Bicontinuous Cubic Liquid Crystal Phases Discovered by High‐Throughput Self‐Assembly Screening of Multi‐Tail Lipidoids

James Jennings and Georg Pabst

Small, 2023, 19
DOI: 10.1002/smll.202206747

Effects of Detergent β-Octylglucoside and Phosphate Salt Solutions on Phase Behavior of Monoolein Mesophases

Daria S. Khvostichenko, Johnathan J.D. Ng, Sarah L. Perry, Monisha Menon and Paul J.A. Kenis

Biophysical Journal, 2013, 105, 1848
DOI: 10.1016/j.bpj.2013.09.009

Cubosome Lipid Nanocarriers As a Drug Delivery Vehicle for Intracellular Mycobacterium tuberculosis Infections

Sampa Sarkar, Brendan Dyett, Biserka Lakic, Andrew S. Ball, Leslie Y. Yeo, Jacinta F. White, Sarvesh Soni, Calum J. Drummond and Charlotte E. Conn

ACS Appl. Mater. Interfaces, 2023, 15, 21819
DOI: 10.1021/acsami.3c00101

Lyotropic liquid crystal phases of monoolein in protic ionic liquids

Stefan Paporakis, Stuart J. Brown, Connie Darmanin, Susanne Seibt, Patrick Adams, Michael Hassett, Andrew V. Martin and Tamar L. Greaves

The Journal of Chemical Physics, 2024, 160
DOI: 10.1063/5.0180420

Close allies in membrane protein research: Cell-free synthesis and nanotechnology

Nadim Shadiac, Yagnesh Nagarajan, Shane Waters and Maria Hrmova

Molecular Membrane Biology, 2013, 30, 229
DOI: 10.3109/09687688.2012.762125

Predicting the Effect of Lipid Structure on Mesophase Formation during in Meso Crystallization

Tu C. Le, Charlotte E. Conn, Frank R. Burden and David A. Winkler

Crystal Growth & Design, 2013, 13, 3126
DOI: 10.1021/cg400513y

Computational Modeling and Prediction of the Complex Time-Dependent Phase Behavior of Lyotropic Liquid Crystals under in Meso Crystallization Conditions

Tu C. Le, Charlotte E. Conn, Frank R. Burden and David A. Winkler

Crystal Growth & Design, 2013, 13, 1267
DOI: 10.1021/cg301730z

Sensitivity of Nanostructure in Charged Cubosomes to Phase Changes Triggered by Ionic Species in Solution

Qingtao Liu, Yao-Da Dong, Tracey L. Hanley and Ben J. Boyd

Langmuir, 2013, 29, 14265
DOI: 10.1021/la402426y

Using Machine Learning To Predict the Self-Assembled Nanostructures of Monoolein and Phytantriol as a Function of Temperature and Fatty Acid Additives for Effective Lipid-Based Delivery Systems

Tu C. Le and Nhiem Tran

ACS Appl. Nano Mater., 2019, 2, 1637
DOI: 10.1021/acsanm.9b00075

Polarisation and rheology characterisation of monoolein/water liquid crystal dynamical behaviour during high-viscosity injector extrusion

Connie Darmanin, Firoozeh Babayekhorasani, Andrew Formosa, Patrick Spicer and Brian Abbey

Journal of Colloid and Interface Science, 2024, 653, 1123
DOI: 10.1016/j.jcis.2023.09.093

Biocompatible Mesoporous and Soft Nanoarchitectures

Angelina Angelova, Borislav Angelov, Rada Mutafchieva and Sylviane Lesieur

J Inorg Organomet Polym, 2015, 25, 214
DOI: 10.1007/s10904-014-0143-8

Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay Between Lipid Molecular Structure, Mesophase Structure and Properties, and Crystallogenesis

Alexandru Zabara, Thomas G. Meikle, Raphael Trenker, Shenggen Yao, Janet Newman, Thomas S. Peat, Frances Separovic, Charlotte E. Conn, Melissa J. Call, Matthew E. Call, Ehud M. Landau and Calum J. Drummond

Crystal Growth & Design, 2017, 17, 5667
DOI: 10.1021/acs.cgd.7b00519

Observations of phase changes in monoolein during high viscous injection

Daniel J. Wells, Peter Berntsen, Eugeniu Balaur, Cameron M. Kewish, Patrick Adams, Andrew Aquila, Jack Binns, Sébastien Boutet, Hayden Broomhall, Carl Caleman, Andrew Christofferson, Charlotte E. Conn, Caroline Dahlqvist, Leonie Flueckiger, Francisco Gian Roque, Tamar L. Greaves, Majid Hejazian, Mark Hunter, Marjan Hadian Jazi, H. Olof Jönsson, Sachini Kadaoluwa Pathirannahalage, Richard A. Kirian, Alex Kozlov, Ruslan P. Kurta, Hugh Marman, Derek Mendez, Andrew Morgan, Keith Nugent, Dominik Oberthuer, Harry Quiney, Juliane Reinhardt, Saumitra Saha, Jonas A. Sellberg, Raymond Sierra, Max Wiedorn, Brian Abbey, Andrew V. Martin and Connie Darmanin

J Synchrotron Rad, 2022, 29, 602
DOI: 10.1107/S1600577522001862

Fluctuation X-ray diffraction reveals three-dimensional nanostructure and disorder in self-assembled lipid phases

Andrew V. Martin, Alexander Kozlov, Peter Berntsen, Francisco Gian Roque, Leonie Flueckiger, Saumitra Saha, Tamar L. Greaves, Charlotte E. Conn, Adrian M. Hawley, Timothy M. Ryan, Brian Abbey and Connie Darmanin

Commun Mater, 2020, 1
DOI: 10.1038/s43246-020-0044-z

Effect of Lipidic Cubic Phase Structure on Functionality of the Dopamine 2L Receptor: Implications for in Meso Crystallization

Connie Darmanin, Sampa Sarkar, Laura Castelli and Charlotte E. Conn

Crystal Growth & Design, 2016, 16, 5014
DOI: 10.1021/acs.cgd.6b00576

Effects of Cations on the Behaviour of Lipid Cubic Phases

Christopher Brasnett, Georgia Longstaff, Laura Compton and Annela Seddon

Sci Rep, 2017, 7
DOI: 10.1038/s41598-017-08438-4

Advances in drug delivery and medical imaging using colloidal lyotropic liquid crystalline dispersions

Xavier Mulet, Ben J. Boyd and Calum J. Drummond

Journal of Colloid and Interface Science, 2013, 393, 1
DOI: 10.1016/j.jcis.2012.10.014

Exploring the in meso crystallization mechanism by characterizing the lipid mesophase microenvironment during the growth of single transmembrane α-helical peptide crystals

Leonie van 't Hag, Konstantin Knoblich, Shane A. Seabrook, Nigel M. Kirby, Stephen T. Mudie, Deborah Lau, Xu Li, Sally L. Gras, Xavier Mulet, Matthew E. Call, Melissa J. Call, Calum J. Drummond and Charlotte E. Conn

Phil. Trans. R. Soc. A., 2016, 374, 20150125
DOI: 10.1098/rsta.2015.0125

In Meso Crystallization: Compatibility of Different Lipid Bicontinuous Cubic Mesophases with the Cubic Crystallization Screen in Aqueous Solution

Leonie van ’t Hag, Connie Darmanin, Tu C. Le, Stephen Mudie, Charlotte E. Conn and Calum J. Drummond

Crystal Growth & Design, 2014, 14, 1771
DOI: 10.1021/cg4018954

Modulating the release of pharmaceuticals from lipid cubic phases using a lipase inhibitor

Michele Dully, Christopher Brasnett, Ahmed Djeghader, Annela Seddon, John Neilan, David Murray, James Butler, Tewfik Soulimane and Sarah P. Hudson

Journal of Colloid and Interface Science, 2020, 573, 176
DOI: 10.1016/j.jcis.2020.04.015

High-Throughput Production and Structural Characterization of Libraries of Self-Assembly Lipidic Cubic Phase Materials

Connie Darmanin, Charlotte E. Conn, Janet Newman, Xavier Mulet, Shane A. Seabrook, Yi-Lynn Liang, Adrian Hawley, Nigel Kirby, Joseph N. Varghese and Calum J. Drummond

ACS Comb. Sci., 2012, 14, 247
DOI: 10.1021/co2001718