Issue 10, 2016

Towards taxane analogues synthesis by dienyne ring closing metathesis

Abstract

Herein we report the facile construction of taxadiene analogues by ring closing metathesis of dienynes built on a cyclohexenone with a natural configuration at C1 and its further transformation to incorporate most of the key functional groups of taxol.

Graphical abstract: Towards taxane analogues synthesis by dienyne ring closing metathesis

Supplementary files

Article information

Article type
Research Article
Submitted
01 ஜூலை 2016
Accepted
17 ஆகஸ்ட் 2016
First published
18 ஆகஸ்ட் 2016

Org. Chem. Front., 2016,3, 1331-1336

Towards taxane analogues synthesis by dienyne ring closing metathesis

S. Pérez-Estrada, N. Sayar and J. R. Granja, Org. Chem. Front., 2016, 3, 1331 DOI: 10.1039/C6QO00321D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements