Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein

J. Jorda; D. J. Leibly; M. C. Thompson; T. O. Yeates

doi:10.1039/C6CC00851H

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein†

J. Jorda,^a D. J. Leibly,^ab M. C. Thompson^b and T. O. Yeates*^ab

Author affiliations

* Corresponding authors

^a UCLA-DOE Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095, USA
E-mail: yeates@mbi.ucla.edu

^b Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA

Abstract

We report the crystal structure of a novel 60-subunit dodecahedral cage that results from self-assembly of a re-engineered version of a natural protein (PduA) from the Pdu microcompartment shell. Biophysical data illustrate the dependence of assembly on solution conditions, opening up new applications in microcompartment studies and nanotechnology.

This article is part of the themed collection: Foldamers

Download options Please wait...

Supplementary files

Supplementary information PDF (387K)

Article information

DOI: https://doi.org/10.1039/C6CC00851H
Article type: Communication
Submitted: 27 ஜனவரி 2016
Accepted: 09 மார்ச் 2016
First published: 09 மார்ச் 2016

Download Citation

Chem. Commun., 2016,52, 5041-5044

Permissions

Request permissions

Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein

J. Jorda, D. J. Leibly, M. C. Thompson and T. O. Yeates, Chem. Commun., 2016, 52, 5041 DOI: 10.1039/C6CC00851H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein

Social activity

Search articles by author

Spotlight

Advertisements