Orthogonal strategy for the synthesis of dual-functionalised β3-peptide based hydrogels

Abstract

We have described a new class of hydrogelator based on helical β³-peptides carrying a bioactive payload. The β³-peptides self-assemble in aqueous solution to form a nanofibrous mesh resulting in a stable hydrogel. The simple design provides the versatility for attaching different functional payloads to the β³-peptide scaffold to develop new materials.