A straightforward protocol for the synthesis of 3-fluoroallyl alcohols via fluorine-hydrogen bonding promoted gold catalyzed hydrofluorination using Et3N·3HF under acidic additive-free conditions has been developed.
The hydrofluorination of enynoates has been developed for the synthesis of fluorinated dienoates.
A gold-catalyzed hydrofluorination of terminal alkynes using potassium bifluoride (KHF2) as a cheaper, safer, and water-free fluoride source, is reported.
A process to shuttle HF from a fluoroalkane to alkynes has been developed. The consecutive dehydrofluorination and hydrofluorination steps are catalysed by an amorphous zirconium chlorofluoride at room temperature.
This review carefully summarizes the advances achieved in catalytic hydrofunctionalization of ynamides and is categorized by the bond formation type including C−C, C−X, C−O, C−N, C−S, C−P, C−Si, and C−Ge bonds.