This review describes the chemistry, biosynthesis, and biological activity of ophiobolin A and sphaeropsidin A, two phytotoxic terpenes with potential anticancer activity, and that of their natural analogues and derivatives.
An efficient 8- and 10-step divergent asymmetric synthesis of aspilactonol F and aspiketolactonol has been achieved using ring-closing metathesis as the key step.
Ten-membered lactones (TMLs) are an interesting and diverse group of natural polyketides that are abundant in fungi and, to a lesser extent, in bacteria, marine organisms, and insects.
Cytochalasans are fungal natural products with diverse structures and biomedical potential. This review explores their diversity, biosynthesis, pharmacokinetics, drug-likeness, and therapeutic potential.
This review article provides an intensive state-of-the-art over the period 2000–2022 centred around the discovery, classifications, biosynthetic pathways and therapeutic potentialities of 351 structurally diverse fungal containing-isocoumarins.