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From monomers to pentamers, diverse antimicrobial benzofuran polyketides from marine-derived Striaticonidium cinctum

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Trends in metabolite discovery from Actinomycetes

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Describing the complex chemistry of benthic seawater: from exometabolite sampling strategies to MS-based metabolomics

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The molecular complexity of terpene biosynthesis in red algae: current state and future perspectives

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Significance of research on natural products from marine-derived Aspergillus species as a source against pathogenic bacteria

Bin Wang, Jin Cai, Longtao Huang, Yonghao Chen, Ruoxi Wang, Mengyao Luo, Meng Yang, Mohan Zhang, Nasihat, Guangying Chen, Guolei Huang and Caijuan Zheng

Front. Microbiol., 2024, 15
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Ceratinadin G, a new psammaplysin derivative possessing a cyano group from a sponge of the genus Pseudoceratina

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Meroterpenoids from Marine Sponge Hyrtios sp. and Their Anticancer Activity against Human Colorectal Cancer Cells

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Marine Drugs, 2024, 22, 183
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Marine-derived compounds applied in osteoarthritis: function, challenges and future prospects

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Discovery of Polyketides and Alkaloids From the Mangrove Endophytic Fungus Diaporthe sp. and Their Anti‐Osteoclastogenic Bioactivities

Humu Lu, Yuyao Feng, Miaoping Lin, Xiang Yu, Yonghong Liu, Yanhui Tan and Xiaowei Luo

Chemistry & Biodiversity, 2025, 22
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Antibacterial activity and mechanism of polyketides from the marine-derived fungus Talaromyces sp.

Ruiyun Huo, Guangrong Zi, Dongxiao Shi, Ying Shi, Jinwei Ren, Kui Hong and Ling Liu

Phytochemistry, 2025, 239, 114606
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Induced production of defensive secondary metabolites from Aspergillus fumigatiaffinis by co-culture with Aspergillus alabamensis

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Oceanic Breakthroughs: Marine-Derived Innovations in Vaccination, Therapy, and Immune Health

Chiara Gamberi, Chad L. Leverette, Alexis C. Davis, Moayad Ismail, Ilaria Piccialli, Nicola Borbone, Giorgia Oliviero, Caterina Vicidomini, Rosanna Palumbo and Giovanni N. Roviello

Vaccines, 2024, 12, 1263
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Marine actinomycetes: a hidden treasure trove for antibacterial discovery

Chengqian Pan, Syed Shams ul Hassan, Muhammad Ishaq, Shikai Yan and Huizi Jin

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Marine Natural Products in Inflammation‐Related Diseases: Opportunities and Challenges

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Purpuramine R, a New Bromotyrosine Isolated from Pseudoceratina cf. verrucosa Collected in the Kingdom of Tonga

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Marine Drugs, 2025, 23, 186
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Metabolites from Marine Macroorganisms of the Red Sea Acting as Promoters or Inhibitors of Amylin Aggregation

Mawadda Alghrably, Mohamed A. Tammam, Aikaterini Koutsaviti, Vassilios Roussis, Xabier Lopez, Giulia Bennici, Abeer Sharfalddin, Hanan Almahasheer, Carlos M. Duarte, Abdul-Hamid Emwas, Efstathia Ioannou and Mariusz Jaremko

Biomolecules, 2024, 14, 951
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New methyl compounds using the predicted data mining approach (PDMA), coupled with the biotransformation of Streptomyces peucetius O -methyltransferase

Te-Sheng Chang, Hsiou-Yu Ding, Jiumn-Yih Wu, Chuan-Che Lee, Ziting Yang, Yu-Chuan Liu and Tzi-Yuan Wang

Biocatalysis and Biotransformation, 2025, 43, 84
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Curvulomycin E, a New Resorcylic Acid Lactone From the Beibu Gulf Coral‐Derived Fungus Curvularia lunata GXIMD 02512

Guihua Yang, Xinjian Qu, Hong Zhang, Chaonan Wang, Miaoping Lin, Xin Qi, Chenghai Gao, Yonghong Liu and Xiaowei Luo

Magnetic Reson in Chemistry, 2025, 63, 777
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Cellular and molecular microbial diversity of the mediterranean sponge Agelas oroides (Demospongiae, Agelasida)

César Ruiz, Jean Vacelet, Flore Corallo, Vincent Dubut, Cécile Chemin, Charlotte Simmler and Alexander Ereskovsky

Mar Biol, 2025, 172
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New Indole Alkaloids from the Fungus Talaromyces assiutensis JTY2

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Chemistry & Biodiversity, 2024, 21
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Heterocycles and a Sorbicillinoid from the Coral-Derived Fungus Penicillium chrysogenum

Junjie Yang, Yuan Zong, Cili Wang, Kai Li, Yue Zhang and Pinglin Li

Marine Drugs, 2024, 22, 517
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Spongia Sponges: Unabated Sources of Novel Secondary Metabolites

Qi-Bin Yang and Lin-Fu Liang

Marine Drugs, 2024, 22, 213
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Discovery of new aphidicolin diterpenoids from the deep-sea-derived fungus Botryotinia fuckeliana with cytotoxic activity against human bladder cancer cells

Siwen Niu, Shuhuan Huang, Menglei Shi, Zhuhua Luo, Zongze Shao, Bihong Hong and Wenjing Tian

Bioorganic Chemistry, 2025, 157, 108311
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Orally Bioavailable and Site-Selective Covalent STING Inhibitor Derived from a Macrocyclic Marine Diterpenoid

Guang-Hao Niu, Wan-Chi Hsiao, Po-Hsun Lee, Li-Guo Zheng, Yu-Shao Yang, Wei-Cheng Huang, Chih-Chien Hsieh, Tai-Yu Chiu, Jing-Ya Wang, Ching-Ping Chen, Chen-Lung Huang, May-Su You, Yi-Ping Kuo, Chien-Ming Wang, Zhi-Hong Wen, Guann-Yi Yu, Chiung-Tong Chen, Ya-Hui Chi, Chun-Wei Tung, Shu-Ching Hsu, Teng-Kuang Yeh, Ping-Jyun Sung, Mingzi M. Zhang and Lun Kelvin Tsou

J. Med. Chem., 2025, 68, 5471
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New Zosteropenillines and Pallidopenillines from the Seagrass-Derived Fungus Penicillium yezoense KMM 4679

Elena V. Leshchenko, Ekaterina A. Chingizova, Alexandr S. Antonov, Nadezhda P. Shlyk, Gleb V. Borkunov, Dmitrii V. Berdyshev, Viktoria E. Chausova, Natalya N. Kirichuk, Yuliya V. Khudyakova, Artur R. Chingizov, Anatoly I. Kalinovsky, Roman S. Popov, Natalya Yu. Kim, Ksenia A. Chadova, Ekaterina A. Yurchenko, Marina P. Isaeva and Anton N. Yurchenko

Marine Drugs, 2024, 22, 317
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A new diphenyl ether with insecticidal activity from the mangrove endophytic fungus Aspergillus sp. GXNU-DY2-12

Meijing Tan, Shichao Ju, Fan He, Wenjun Li, Youquan Wei, Weifeng Xu, Ruiyun Yang and Xishan Huang

Natural Product Research, 2025, 1
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Genome mining and biosynthetic pathways of marine-derived fungal bioactive natural products

Caihua Han, Anjing Song, Yueying He, Liu Yang, Litong Chen, Wei Dai, Qilin Wu and Siwen Yuan

Front. Microbiol., 2024, 15
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Stonikacidin A, an Antimicrobial 4-Bromopyrrole Alkaloid Containing L-Idonic Acid Core from the Northwestern Pacific Marine Sponge Lissodendoryx papillosa

Kseniya M. Tabakmakher, Tatyana N. Makarieva, Yuri E. Sabutski, Maxim S. Kokoulin, Alexander S. Menshov, Roman S. Popov, Alla G. Guzii, Larisa K. Shubina, Ekaterina A. Chingizova, Artur R. Chingizov, Ekaterina A. Yurchenko, Sergey N. Fedorov, Boris B. Grebnev, Gunhild von Amsberg, Sergey A. Dyshlovoy, Natalia V. Ivanchina and Pavel S. Dmitrenok

Marine Drugs, 2024, 22, 396
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Cytotoxic Pentaketide-Sesquiterpenes from the Marine-Derived Fungus Talaromyces variabilis M22734

Lingzhi Tang, Jinmei Xia, Zhongwei Chen, Xiaohui Wu, Guangyu Li, Qiliang Lai, Zongze Shao, Weiyi Wang and Xuan Hong

Marine Drugs, 2024, 22, 274
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Natural Products from Marine-Derived Fungi with Anti-Inflammatory Activity

Yikang Qiu, Shiji Chen, Miao Yu, Jueying Shi, Jiayu Liu, Xiaoyang Li, Jiaxing Chen, Xueping Sun, Guolei Huang and Caijuan Zheng

Marine Drugs, 2024, 22, 433
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An Overview of Secondary Metabolites from Soft Corals of the Genus Capnella over the Five Decades: Chemical Structures, Pharmacological Activities, NMR Data, and Chemical Synthesis

Can-Qi Liu, Qi-Bin Yang, Ling Zhang and Lin-Fu Liang

Marine Drugs, 2024, 22, 402
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Avellanin A Has an Antiproliferative Effect on TP-Induced RWPE-1 Cells via the PI3K-Akt Signalling Pathway

Chang Xu, Guangping Cao, Hong Zhang, Meng Bai, Xiangxi Yi and Xinjian Qu

Marine Drugs, 2024, 22, 275
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Recent Discovery of Nitrogen Heterocycles from Marine-Derived Aspergillus Species

Jueying Shi, Miao Yu, Weikang Chen, Shiji Chen, Yikang Qiu, Zhenyang Xu, Yi Wang, Guolei Huang and Caijuan Zheng

Marine Drugs, 2024, 22, 321
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A Marine‐Derived Small Molecule Inhibits Prostate Cancer Growth by Promoting Endoplasmic Reticulum Stress Induced Apoptosis and Autophagy

Mao Ding, Mu He, Dan Li, Shuaishuai Ding, Chenjia Dong, Hongchao Zhao, Huajie Song, Kui Hong and Hengcheng Zhu

Phytotherapy Research, 2024, 38, 6004
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Structural Diversity and Bioactivities of Marine Fungal Terpenoids (2020–2024)

Minghua Jiang, Senhua Chen, Zhibin Zhang, Yiwen Xiao, Du Zhu and Lan Liu

Marine Drugs, 2025, 23, 300
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Exploring the mechanism of Synechococcus sp. XM-24 in gastric cancer treatment via network pharmacology and molecular docking

Jiayi Li, Yamei Ma, Longzhi Guo, Junhong Liu, Lin Li and Mohd Rehan

PLoS One, 2025, 20, e0326664
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Marine-Origin Polysaccharides and Their Chemically Modified Derivatives as Sources of Advanced Biofunctional Materials for Biomedical Applications

Vera Sousa, Luís P. G. Monteiro, Djenisa H. A. Rocha, João M. M. Rodrigues, João Borges and João F. Mano

Biomacromolecules, 2025, 26, 4735
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A Novel Lactam and Two Rare Mycophenolic Acid Derivatives from the Fungus Penicillium Sclerotiorum JBHL321

Yue Wang, Xue‐Ming Zhou, Jin‐feng Du, Xue‐Feng Xu and Xin‐Ming Song

Chemistry & Biodiversity, 2025, 22
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Aspergillicin I, new depsipeptide from the marine-derived fungal strain Aspergillus uvarum BTBU20212048

Ran Chen, Kai Zhang, Tong Xu, Xiuli Xu and Fuhang Song

Natural Product Research, 2025, 1
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Recent Advances in Natural Products Derived from Marine Echinoderms and Endophytic Microbes: Chemical Insights and Therapeutic Potential

Shuangyu Li, Yan Xiao, Qiang Li, Mingzhi Su, Yuewei Guo and Xin Jin

Marine Drugs, 2025, 23, 33
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Nutraceutical and Medicinal Importance of Marine Molluscs

Yvan Anderson Tchangoue Ngandjui, Tsotlhe Trinity Kereeditse, Ilunga Kamika, Lawrence Mzukisi Madikizela and Titus Alfred Makudali Msagati

Marine Drugs, 2024, 22, 201
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Antibacterial and antibiofilm effects of invasive corals Tubastraea coccinea and Tubastraea tagusensis

Raphael de Mello Carpes, Thiago José de Souza Barboza, Ana Cláudia de Paula Rosa, Simon John Garden, Beatriz Grosso Fleury, Joel Christopher Creed and Israel Felzenszwalb

Academia Biology, 2025, 3
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Diterpenoids of Marine Organisms: Isolation, Structures, and Bioactivities

Qi Shi, Shujie Yu, Manjia Zhou, Peilu Wang, Wenlong Li, Xin Jin, Yiting Pan, Yunjie Sheng, Huaqiang Li, Luping Qin and Xiongyu Meng

Marine Drugs, 2025, 23, 131
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Three new polyketones from mangrove endophytic fungus aspergillus sp. HMGh1–1 and their insecticidal activity

Wenjun Li, Meijing Tan, Shichao Ju, Fan He, Jiao Wu, Youquan Wei, Jinyu Wen, Baoliang Li and Xishan Huang

Fitoterapia, 2025, 186, 106803
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Marine natural products as an important source of bioactive substances for non-alcoholic fatty liver disease management

Menglei Shi, Sisi Chen, Yutong Feng, Shiyuan Wang, Yuyu Xia and Jianlin He

Front. Mar. Sci., 2025, 11
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Bioactive Sesterterpenoids from the Mangrove-Derived Aspergillus sp. GXIMD 03023

Jia-Li He, Yu Wang, Xiang-Xi Yi, Yu-Man Gan, Yong-Hong Liu, Cheng-Hai Gao, Kai Liu and Meng Bai

J. Nat. Prod., 2025, 88, 1201
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Thuwalamides A–E: Polychlorinated amides from the marine sponge Lamellodysidea herbacea collected from the Saudi Arabian Red Sea

Mohamed A. Tammam, Nikolaos Tsoureas, Dafni-Ioanna Diakaki, Carlos M. Duarte, Vassilios Roussis and Efstathia Ioannou

Phytochemistry, 2025, 230, 114315
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Marine actinomycetes-derived angucyclines and angucyclinones with biosynthesis and activity--past 10 years (2014–2023)

Xiao Xu, Xiaofei Huang and Wenhua Xu

European Journal of Medicinal Chemistry, 2025, 283, 117161
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Harnessing marine bacteria for next-gen antibiotics: potent inhibition of S. aureus and Riemerella anatipestifer through in vitro, omics, and chemoinformatics approach with enhanced production of secondary metabolites through zinc sulfate

Syed Shams ul Hassan and Huizi Jin

Front. Mar. Sci., 2025, 11
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Bioactive Alkaloids from the Mangrove-Derived Fungus Nigrospora oryzae SYSU-MS0024

Xiaokun Chen, Senhua Chen, Heng Guo, Xin Lu, Hongjie Shen, Lan Liu, Li Wang, Bin Chen, Yi Zhang and Yayue Liu

Marine Drugs, 2024, 22, 214
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Antioomycete Activity and Mechanism of Territrem B, against Phytophthora capsici in Prevention of Phytophthora Blight

Jin Cai, Bin Wang, Ruoxi Wang, Longtao Huang, Mengyao Luo, Yonghao Chen, Mohan Zhang, Meng Yang, Youping Luo, Nasihat, Fengman Yin, Guolei Huang and Caijuan Zheng

J. Agric. Food Chem., 2025, 73, 19386
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Immunomodulatory Compounds from the Sea: From the Origins to a Modern Marine Pharmacopoeia

Edoardo Andrea Cutolo, Rosanna Campitiello, Roberto Caferri, Vittorio Flavio Pagliuca, Jian Li, Spiros Nicolas Agathos and Maurizio Cutolo

Marine Drugs, 2024, 22, 304
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A Review of Sponge-Derived Diterpenes: 2009–2022

Jinmei Xia, Xiangwei Chen, Guangyu Li, Peng Qiu, Weiyi Wang and Zongze Shao

Marine Drugs, 2024, 22, 447
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New antifungal chlorinated orsellinic aldehydes from the deep-sea-derived fungus Acremonium sclerotigenum LW14

Ruiyun Huo, Yu Tu, Chang Liu, Guangrong Zi, Ying Shi, Jinwei Ren, Lei Cai and Ling Liu

Mycology, 2025, 1
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Mechanisms of fatigue and molecular diagnostics: The application of bioactive compounds in fatigue relief research

Xinxin Si, Yanyan Si, Zhen Lu, Tian Zhong, Ying Xiao, Zhenyu Wang and Xi Yu

Food Bioscience, 2025, 68, 106523
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Antioomycete activity and mechanism of neoechinulin A from the marine fungus Aspergillus amstelodami 012393 against Phytophthora capsici: neoechinulin A against Phytophthora capsici

Jin Cai, Fengman Yin, Guojun Zhou, Meng Yang, Mohan Zhang, Yonghao Chen, Sirong Li, Youping Luo, Mary Krinzy Charm Bañadera, Guolei Huang and Caijuan Zheng

Pest Management Science, 2025
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Biological Activities of Aspergillus niger MF6: Antimicrobial, Antioxidant, and Cytotoxic Potential of Marine-Derived Fungus Metabolites

Moaz M. Hamed, Mohamed A. A. Abdrabo, Lamis Sh. Abdelfattah and Yasser A. Geneid

Curr Microbiol, 2025, 82
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Marine natural products as potential anti-Pseudomonas aeruginosa agents: challenges and advances

Liu-Xia Lv, Jun-Na Yin, Yi-Lin Sun, Mei-Yan Wei, Wen-Qing Jiang, Yu-Cheng Gu, Xiao-Ping Yang and Chang-Lun Shao

European Journal of Medicinal Chemistry, 2025, 292, 117670
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Discovery of ianthelliformisamines D–G from the sponge Suberea ianthelliformis and the total synthesis of ianthelliformisamine D

Sasha Hayes, Yaoying Lu, Bernd H A Rehm and Rohan A Davis

Beilstein J. Org. Chem., 2024, 20, 3205
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Peripheral neuroprotective potential and toxicological profile of fascaplysin in zebrafish models

Ki-Hoon Park, Youngbuhm Huh, Hyung-Joo Chung, Hiroyuki Konishi, Junyang Jung and Na Young Jeong

Anat Cell Biol, 2025, 58, 274
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Secondary Metabolites from the Mangrove Ecosystem-Derived Fungi Penicillium spp.: Chemical Diversity and Biological Activity

Guojun Zhou, Jin Cai, Bin Wang, Wenjiao Diao, Yu Zhong, Shaodan Pan, Weijia Xiong, Guolei Huang and Caijuan Zheng

Marine Drugs, 2024, 23, 7
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A new sesquiterpene with a specialized [4,4] bicyclononane skeleton from the marine-derived fungus Metarhizium sp. P2100

Zhong-Lian Ma, Zhi-Pu Yu, Ling Lv, Zhi-Qing Liu, Chang-Yun Wang and Guang-Shan Yao

Tetrahedron, 2025, 178, 134607
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Cinerols L–R, Anti-inflammatory Meroterpenoids from the Marine Sponge Dysidea cinerea

Ru-Yi Shang, Fan Sun, Xiang-Chao Luo, Bao-Hui Cheng, Jia-Xin Li, Tian-Yong Hu, Dong-Dong Xie, Robert J. Capon, Hou-Wen Lin and Wei-Hua Jiao

J. Nat. Prod., 2025, 88, 926
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Uncommon Diterpenoids with Diverse Frameworks from the South China Sea Sponge Spongia officinalis and Their Anti-inflammatory Activities

Song-Wei Li, Jiao Liu, Zi-Yi Liu, Yan Fu, Li-Gong Yao, Yu-Cheng Gu, Hai-Yan Zhang, Xu-Wen Li and Yue-Wei Guo

J. Org. Chem., 2025, 90, 1950
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One New Quinazoline‐Containing Diketopiperazine Isolated from the Marine‐Sponge‐Derived Fungus Penicillium sp. SCSIO41043

Qinlin Cao, Xiaoyan Pang, Zhiyun Chen, Junfeng Wang, Xuefeng Zhou, Bin Yang and Yonghong Liu

Chemistry & Biodiversity, 2025, 22
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Retrobisabolane A, a Novel Bisabolane‐Derived Sesquiterpenoid Isolated from Deep‐Sea‐Derived Fungus Retroconis fusiformis MCCC 3A00792

Xin Liu, Yinghui Lv, Jianlin He, Bihong Hong, Zongze Shao, Miao Yu and Siwen Niu

Chemistry & Biodiversity, 2024, 21
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Isolation of a new natural bromopyrrole alkaloid agenakasine, a biosynthetically related metabolite laughine, and norzooanemonin from a marine sponge Agelas nakamurai

Chung-Wei Fu, Atallah F. Ahmed, Lin Chiang, Shu-Fen Chiou, Hui-Chun Wang and Jyh-Horng Sheu

Phytochemistry Letters, 2025, 68, 102975
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Molecular networking-guided isolation of linearly fused prenylated indole diketopiperazine alkaloids from a marine-derived fungus Aspergillus sp. MG35-18 and their anti-inflammatory effects

Xiaojun Dai, Zixuan Xia, Changrong Lai, Xunuo Li, Jieyuan Tu, Danmei Tian, Bin Wu and Jinshan Tang

Fitoterapia, 2025, 185, 106733
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Recent Advances in Anti-Inflammatory Compounds from Marine Microorganisms

Guihua Yang, Miaoping Lin, Kumaravel Kaliaperumal, Yaqi Lu, Xin Qi, Xiaodong Jiang, Xinya Xu, Chenghai Gao, Yonghong Liu and Xiaowei Luo

Marine Drugs, 2024, 22, 424
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Molecular Networking Reveals Indolo-Sesquiterpene Hybrids from the Marine-Derived Fungus Aspergillus terreus N4-9

Min Chen, Bao-Cong Hao, Ruo-Nan Ji, Long Chen, Xiao-Jian Zhou, Li Shen, Juan-Juan Wang and Li-Kui Zhang

J. Nat. Prod., 2025, 88, 1526
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Recent Advances of Bioactive Marine Natural Products in Drug Discovery

Qun Zhang, Liuxia Lv, Wenhui Wang, Meiyan Wei, Yucheng Gu and Changlun Shao

J. Ocean Univ. China, 2024, 23, 1297
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ECONOMIC IMPORTANCE OF MOLLUSCAN

Md. Varis

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New Hydroxyphenylacetic Acids and α‐Pyrone Derivative from the Deep‐Sea Cold Seep Sediment‐Derived Fungus Penicillium corylophilum CS‐682

Chi‐Sheng Zhu, Xiao‐Ming Li, Sui‐Qun Yang, Yi‐Wei Liu, Bin‐Gui Wang and Xin Li

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Sesquiterpenoids from the hydrothermal vent sediment derived fungus Penicillium sp. JWM79-5-1 with antithrombotic and pro-angiogenic activities

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Mar Life Sci Technol, 2025
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Isoechinulin-Type Diketopiperazines with Anti-monocyte Adhesion Activities from a Sponge-Associated Aspergillus sp

Weihao Chen, Jianheng Ma, Mengjing Cong, Xiaoyan Pang, Xiuping Lin, Shengrong Liao, Bin Yang, Xuefeng Zhou, Junfeng Wang and Yonghong Liu

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Synthesis of a Conformationally Fixed Bicyclomarin Derivative

Jennifer Greve, Alexander F. Kiefer and Uli Kazmaier

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A Demonstration of Bromoform-Producing Gametophyte Culture for a Red Alga, Asparagopsis taxiformis in Laboratory Conditions

Ryuya Matsuda and Kazuyoshi Kuwano

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Kallopterolides A–I, a New Subclass of seco-Diterpenes Isolated from the Southwestern Caribbean Sea Plume Antillogorgia kallos

Jeffrey Marrero, Luis A. Amador, Ivan M. Novitskiy, Andrei G. Kutateladze and Abimael D. Rodríguez

Molecules, 2024, 29, 2493
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