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Lab Chip, 2024, 24, 1030
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Vascularized human brain organoid on-chip

Sin Yen Tan, Xiaohan Feng, Lily Kwan Wai Cheng and Angela Ruohao Wu

Lab Chip, 2023, 23, 2693
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Self-assembled human arteriole-on-a-chip for arterial functionality testing and disease modeling

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Lab Chip, 2025
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Vascular microphysiological systems (MPS): biologically relevant and potent models

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Lab Chip, 2025, 25, 4221
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Pericytes and shear stress each alter the shape of a self-assembled vascular network

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Lab Chip, 2023, 23, 306
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Rocker or pump? Transcriptomic response of endothelial cells exposed to peristaltic pump-based unidirectional flow vs. rocker-induced bidirectional flow

Negar Vahdani, Prateek Arora, Lisette van Os, Denise Ackermann, Nadia Mercader and Olivier T. Guenat

Lab Chip, 2025
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Understanding drug nanocarrier and blood–brain barrier interaction based on a microfluidic microphysiological model

Yuanyuan Fan, Chang Xu, Ning Deng, Ze Gao, Zhongyao Jiang, Xiaoxiao Li, Yingshun Zhou, Haimeng Pei, Lu Li and Bo Tang

Lab Chip, 2023, 23, 1935
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Convective forces contribute to post‐traumatic degeneration after spinal cord injury

Hoi Y. Kwon, Christopher Streilein and R. Chase Cornelison

Bioengineering & Transla Med, 2025, 10
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Perfusion in Organ-on-Chip Models and Its Applicability to the Replication of Spermatogenesis In Vitro

Sholom Shuchat, Gilad Yossifon and Mahmoud Huleihel

IJMS, 2022, 23, 5402
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Oxygen gradients dictate angiogenesis but not barriergenesis in a 3D brain microvascular model

Kiet A. Tran, Abigail Baldwin‐Leclair, Brandon J. DeOre, Morgan Antisell and Peter A. Galie

Journal Cellular Physiology, 2022, 237, 3872
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A User-Centric 3D-Printed Modular Peristaltic Pump for Microfluidic Perfusion Applications

Jorge A. Cataño, Steven Farthing, Zeus Mascarenhas, Nathaniel Lake, Prasad K. D. V. Yarlagadda, Zhiyong Li and Yi-Chin Toh

Micromachines, 2023, 14, 930
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Critical design parameters to develop biomimetic organ-on-a-chip models for the evaluation of the safety and efficacy of nanoparticles

Mahmoud Abdelkarim, Luis Perez-Davalos, Yasmin Abdelkader, Amr Abostait and Hagar I. Labouta

Expert Opinion on Drug Delivery, 2023, 20, 13
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Evaluating Morphology and Functionality of On-Chip Vascular Network Derived from Human Umbilical Vein Endothelial Cells (HUVECs) during Long-Term Culture

Atsuya Kitada, Maneesha Shaji, Taiga Irisa, Kazuya Fujimoto, Stanislav L. Karsten and Ryuji Yokokawa

IEEJ Trans. SM, 2023, 143, 82
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Integrating functional vasculature into organoid culture: A biomechanical perspective

Shun Zhang, Ellen L. Kan and Roger D. Kamm

APL Bioengineering, 2022, 6
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Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery

Fatemeh Davodabadi, Seyedeh Fatemeh Sajjadi, Mohammad Sarhadi, Shaghayegh Mirghasemi, Mahdieh Nadali Hezaveh, Samin Khosravi, Mahdieh Kamali Andani, Marco Cordani, Mohsen Basiri and Saeid Ghavami

European Journal of Pharmacology, 2023, 958, 176013
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Personalized intermittent pneumatic calf compression frequency for augmenting foot blood perfusion: The optimized effect and a personalized mode predicting method

Bitian Wang, Yawei Wang, Hanhao Liu, Zhujun Sun, Junchao Guo, Fang Pu, Guifu Wu and Yubo Fan

Journal of Biomechanics, 2023, 160, 111820
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Converging neural-centric and mechano-regulation in organoid modeling for system biology and medicine

Jiyuan Tang, Zitian Wang, Davit Khutsishvili, Yu Zhu, Jiawei Li, Feifei Yu, Gan Sang, Junhong Zeng, Ziqi Yi, Yi-chun Huang, Xiangsai Li, Peter E Lobie and Shaohua Ma

TIME, 2024, 2, 100076
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Limitations of human brain organoids to study neurodegenerative diseases: a manual to survive

Nerea Urrestizala-Arenaza, Sonia Cerchio, Fabio Cavaliere and Chiara Magliaro

Front. Cell. Neurosci., 2024, 18
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Towards Novel Biomimetic In Vitro Models of the Blood–Brain Barrier for Drug Permeability Evaluation

Inés Mármol, Sara Abizanda-Campo, Jose M. Ayuso, Ignacio Ochoa and Sara Oliván

Bioengineering, 2023, 10, 572
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Acoustofluidic Engineering of Functional Vessel-on-a-Chip

Yue Wu, Yuwen Zhao, Khayrul Islam, Yuyuan Zhou, Saeed Omidi, Yevgeny Berdichevsky and Yaling Liu

ACS Biomater. Sci. Eng., 2023, 9, 6273
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The Edifice of Vasculature-On-Chips: A Focused Review on the Key Elements and Assembly of Angiogenesis Models

Joshua Lim, Hsu-Wei Fang, Sasinan Bupphathong, Po-Chan Sung, Chen-En Yeh, Wei Huang and Chih-Hsin Lin

ACS Biomater. Sci. Eng., 2024, 10, 3548
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Brain‐On‐A‐Chip Based on Human Pluripotent Stem Cell‐Derived Neurons and Astrocytes for Neurotoxicity Testing: Communicative Astrocyte–Neuron DYnamics (CANDY) Chip

Geonho Choi, Han‐Yeol Yang, Sungwoo Cho, Dohyung Kwon, Dong‐Wook Kim and Sungho Ko

Adv Materials Technologies, 2024, 9
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Standardizing designed and emergent quantitative features in microphysiological systems

Dennis M. Nahon, Renée Moerkens, Hande Aydogmus, Bas Lendemeijer, Adriana Martínez-Silgado, Jeroen M. Stein, Milica Dostanić, Jean-Philippe Frimat, Cristina Gontan, Mees N. S. de Graaf, Michel Hu, Dhanesh G. Kasi, Lena S. Koch, Kieu T. T. Le, Sangho Lim, Heleen H. T. Middelkamp, Joram Mooiweer, Paul Motreuil-Ragot, Eva Niggl, Cayetano Pleguezuelos-Manzano, Jens Puschhof, Nele Revyn, José M. Rivera-Arbelaez, Jelle Slager, Laura M. Windt, Mariia Zakharova, Berend J. van Meer, Valeria V. Orlova, Femke M. S. de Vrij, Sebo Withoff, Massimo Mastrangeli, Andries D. van der Meer and Christine L. Mummery

Nat. Biomed. Eng, 2024, 8, 941
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Numerical analysis of a Keller–Segel-Flow model for tumor cell migration

A. Fernandes, J.A. Ferreira and L. Pinto

Mathematics and Computers in Simulation, 2025, 238, 65
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Biomechanical and mechanobiological design for bioprinting functional microvasculature

Dongrui Zhang, Jiangyue Liu, Xiao Liu and Yubo Fan

Applied Physics Reviews, 2025, 12
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Microfluidic Platform with Local Oxygen Sensors Demonstrates That 3D Blood Vessel Networks Exhibit Time‐Dependent Changes in Oxygen Concentrations During Their Formation and Perfusion

Tarek Gensheimer, Stefanie Fuchs, Laura E. de Heus, Kim Vermeul, Torsten Mayr and Andries v.d. Meer

Adv Materials Technologies, 2025
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Vascularized organoid-on-a-chip: design, imaging, and analysis

Tingting Yu, Qihang Yang, Bo Peng, Zhongze Gu and Dan Zhu

Angiogenesis, 2024, 27, 147
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Engineered inflammation-induced neurodevelopmental disorders using a neurovascular-unit-on-a-chip

Rong Zou, Zhengdi Shi, Chengpan Li, Fan Xu, Xucai Zheng, Xiaofang Du, Dabing Huang, Bensheng Qiu and Weiping Ding

Bio-des. Manuf., 2025, 8, 639
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A Transwell-Based Vascularized Model to Investigate the Effect of Interstitial Flow on Vasculogenesis

Pengwei Deng, Mengqian Zhao, Xu Zhang and Jianhua Qin

Bioengineering, 2022, 9, 668
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High‐Scale 3D‐Bioprinting Platform for the Automated Production of Vascularized Organs‐on‐a‐Chip

Anna Fritschen, Nils Lindner, Sebastian Scholpp, Philipp Richthof, Jonas Dietz, Philipp Linke, Zeno Guttenberg and Andreas Blaeser

Adv Healthcare Materials, 2024, 13
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Self-assembling 3D vessel-on-chip model with hiPSC-derived astrocytes

Dennis M. Nahon, Marc Vila Cuenca, Francijna E. van den Hil, Michel Hu, Tessa de Korte, Jean-Philippe Frimat, Arn M.J.M. van den Maagdenberg, Christine L. Mummery and Valeria V. Orlova

Stem Cell Reports, 2024, 19, 946
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Engineering polystyrene microtube-embedded composite hydrogels for tunable vascular morphogenesis

Xianyang Li, Sadia Khan, Liyuan Wang, Yan Chen, Xiang Fang, Yingge Zhou and Ying Wang

Biomed. Mater., 2025, 20, 045030
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Microfluidic Droplet-Assisted Fabrication of Vessel-Supported Tumors for Preclinical Drug Discovery

Yue Wu, Yuwen Zhao, Yuyuan Zhou, Khayrul Islam and Yaling Liu

ACS Appl. Mater. Interfaces, 2023, 15, 15152
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Perfusability and immunogenicity of implantable pre-vascularized tissues recapitulating features of native capillary network

Dhavan Sharma, Archita Sharma, Linghao Hu, Te-An Chen, Sarah Voon, Kayla J. Bayless, Jeremy Goldman, Alex J. Walsh and Feng Zhao

Bioactive Materials, 2023, 30, 184
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Micro/nanosystems for controllable drug delivery to the brain

Mingzhen Tian, Zhichao Ma and Guang-Zhong Yang

The Innovation, 2024, 5, 100548
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A Vascularized Multilayer Chip Reveals Shear Stress-Induced Angiogenesis in Diverse Fluid Conditions

Tao Yue, Huiying Yang, Yue Wang, Ning Jiang, Hongze Yin, Xiaoqi Lu, Na Liu and Yichun Xu

Cyborg Bionic Syst, 2025, 6
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Flow in fetoplacental-like microvessels in vitro enhances perfusion, barrier function, and matrix stability

Marta Cherubini, Scott Erickson, Prasanna Padmanaban, Per Haberkant, Frank Stein, Violeta Beltran-Sastre and Kristina Haase

Sci. Adv., 2023, 9
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Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids

Hongwei Cai, Chunhui Tian, Lei Chen, Yang Yang, Alfred Xuyang Sun, Kyle McCracken, Jason Tchieu, Mingxia Gu, Ken Mackie and Feng Guo

Cell Stem Cell, 2025, 32, 824
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Angiogenesis and Functional Vessel Formation Induced by Interstitial Flow and Vascular Endothelial Growth Factor Using a Microfluidic Chip

Yufang Liu, Jiao Li, Jiasheng Zhou, Xue Liu, Huibing Li, Yao Lu, Bingcheng Lin, Xiaojie Li and Tingjiao Liu

Micromachines, 2022, 13, 225
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Microfluidic Chip-Based Modeling of Three-Dimensional Intestine–Vessel–Liver Interactions in Fluorotelomer Alcohol Biotransformation

Ning Xu, Haifeng Lin, Jin-Ming Lin, Jie Cheng, Peilong Wang and Ling Lin

Anal. Chem., 2023, 95, 17064
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Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells

Taylor Bertucci, Shravani Kakarla, Max A. Winkelman, Keith Lane, Katherine Stevens, Steven Lotz, Alexander Grath, Daylon James, Sally Temple and Guohao Dai

APL Bioengineering, 2023, 7
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Interstitial Flow Promotes the Formation of Functional Microvascular Networks In Vitro through Upregulation of Matrix Metalloproteinase‐2

Shun Zhang, Zhengpeng Wan, Georgios Pavlou, Amy X. Zhong, Liling Xu and Roger D. Kamm

Adv Funct Materials, 2022, 32
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Flow‐IMPACT: A Pumpless, High‐Throughput 3D Cell Culture Platform for Investigation of Synergistic Angiogenic Effects

Seonghyuk Park, Youngtaek Kim, Jungseub Lee, Sangmin Jung, Jongho Hong, Suryong Kim, Seung‐Ryeol Lee, Jiyoung Song, Siwan Park, Young Sun Oh, Jihoon Ko and Noo Li Jeon

Adv Materials Technologies, 2025, 10
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Replacement in angiogenesis research: Studying mechanisms of blood vessel development by animal-free in vitro, in vivo and in silico approaches

Matthias W. Laschke, Yuan Gu and Michael D. Menger

Front. Physiol., 2022, 13
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Bioprinting Vascularized Constructs for Clinical Relevance: Engineering Hydrogel Systems for Biological Maturity

Jeonghyun Son, Siyuan Li and Wonwoo Jeong

Gels, 2025, 11, 636
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Bioengineered perfused human brain microvascular networks enhance neural progenitor cell survival, neurogenesis, and maturation

Max A. Winkelman and Guohao Dai

Sci. Adv., 2023, 9
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A Cost-Effective and Easy to Assemble 3D Human Microchannel Blood–Brain Barrier Model and Its Application in Tumor Cell Adhesion Under Flow

Yunfei Li and Bingmei M. Fu

Cells, 2025, 14, 456
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