Recent advances in centrifugal microfluidics for point-of-care testing

Huijuan Yuan, Zeyu Miao, Chao Wan, Jingjing Wang, Jinzhi Liu, Yiwei Li, Yujin Xiao, Peng Chen and Bi-Feng Liu

Lab Chip, 2025, 25, 1015
DOI: 10.1039/D4LC00779D

A continuous flow PCR array microfluidic chip applied for simultaneous amplification of target genes of periodontal pathogens

Bo Yang, Ping Wang, Zhenqing Li, Chunxian Tao, Qingxiang You, Shinichi Sekine, Songlin Zhuang, Dawei Zhang and Yoshinori Yamaguchi

Lab Chip, 2022, 22, 733
DOI: 10.1039/D1LC00814E

Simultaneous amplification of DNA in a multiplex circular array shaped continuous flow PCR microfluidic chip for on-site detection of bacterial

Bo Yang, Ping Wang, Zhenqing Li, Qingxiang You, Shinichi Sekine, Junshan Ma, Songlin Zhuang, Dawei Zhang and Yoshinori Yamaguchi

Lab Chip, 2023, 23, 2633
DOI: 10.1039/D3LC00274H

Direct count of fluorescent microspheres in a microfluidic chip based on the capillary electrophoresis method

Jing Yang, Zhenqing Li, Dawei Zhang, Yoshinori Yamaguchi and Wen Xiao

Anal. Methods, 2023, 15, 3014
DOI: 10.1039/D3AY00710C

A rapid nucleic acid concentration measurement system with large field of view for a droplet digital PCR microfluidic chip

Jinrong Shen, Jihong Zheng, Zhenqing Li, Yourong Liu, Fengxiang Jing, Xinjun Wan, Yoshinori Yamaguchi and Songlin Zhuang

Lab Chip, 2021, 21, 3742
DOI: 10.1039/D1LC00532D

The thermal cycling methods for rapid PCR

Ruihua Ding, Jiali Zhang and Chang Chen

Critical Reviews in Biotechnology, 2025, 1
DOI: 10.1080/07388551.2025.2540368

Facile prepared microfluidic chip for multiplexed digital RT‐qPCR test

Wenqi Hu, Yidan Zhu, Qu Tang, Xiaolei Ji, Lei Wang, Weijun Ou, Guo Li, Li Wu, Hui Cong and Yuling Qin

Biotechnology Journal, 2024, 19
DOI: 10.1002/biot.202300273

A Portable Continuous-Flow Polymerase Chain Reaction Chip Device Integrated with Arduino Boards for Detecting Colla corii asini

Shyang-Chwen Sheu, Yi-Syuan Song and Jyh-Jian Chen

Micromachines, 2022, 13, 1289
DOI: 10.3390/mi13081289

Portable biosensor-based oral pathogenic bacteria detection for community and family applications

Jieyu Ming, Xin Zeng and Ronghui Zhou

Anal Bioanal Chem, 2023, 415, 5221
DOI: 10.1007/s00216-023-04809-1

Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics

Zheng Li, Xiaojian Xu, Dou Wang and Xingyu Jiang

TrAC Trends in Analytical Chemistry, 2023, 158, 116871
DOI: 10.1016/j.trac.2022.116871

A rapid and low-cost platform for detection of bacterial based on microchamber PCR microfluidic chip

Zhenqing Li, Xiaolu Ma, Zhen Zhang, Xiaoyang Wang, Bo Yang, Jing Yang, Yuan Zeng, Xujun Yuan, Dawei Zhang and Yoshinori Yamaguchi

Biomed Microdevices, 2024, 26
DOI: 10.1007/s10544-024-00699-x

A Cost-Effective Nucleic Acid Detection System Using a Portable Microscopic Device

Chengzhuang Yu, Shanshan Li, Chunyang Wei, Shijie Dai, Xinyi Liang and Junwei Li

Micromachines, 2022, 13, 869
DOI: 10.3390/mi13060869

Construction of a microcavity-based microfluidic chip with simultaneous SERS quantification of dual biomarkers for early diagnosis of Alzheimer's disease

Jianli Sun, Zengliang Shi, Li Wang, Xinyi Zhang, Chunshan Luo, Jianyu Hua, Muyu Feng, Zaozao Chen, Mingliang Wang and Chunxiang Xu

Talanta, 2023, 261, 124677
DOI: 10.1016/j.talanta.2023.124677

High throughput oscillating-flow structure for polymerase chain reaction

Ranran Zhou, Yu Sun, Yunxia Luan, Wenshen Jia, Yang Yu, Jing Yang, Jin Chen and Fengchao Wang

AIP Advances, 2024, 14
DOI: 10.1063/5.0209492

Spatial continuous-flow polymerase chain reaction structure controlled by single-temperature driver

Ranran Zhou, Yanguang Ding, Yu Sun, Jing Yang, Yang Yu, Jianxin Pang, Jin Chen and Fengchao Wang

AIP Advances, 2023, 13
DOI: 10.1063/5.0156420

Present status of microfluidic PCR chip in nucleic acid detection and future perspective

Shiyu Chen, Yucheng Sun, Fangfang Fan, Shulang Chen, Yingrui Zhang, Yi Zhang, Xianli Meng and Jin-Ming Lin

TrAC Trends in Analytical Chemistry, 2022, 157, 116737
DOI: 10.1016/j.trac.2022.116737

Injectable CuS-loaded carboxymethyl and sulfonated chitosan hydrogel with antibacterial and self-healing properties promoting periodontal tissue regeneration

Qingao Wang, Shang Tang, Fangze Guo, Yunqi Feng, Yabo Li, Mengqing Gong, Yu Zhang, Caiyi Zhang, Li Mei, Youbin Wang, Daishuo Zhang, Wen Su and Changqing Yuan

International Journal of Biological Macromolecules, 2025, 310, 143205
DOI: 10.1016/j.ijbiomac.2025.143205

A continuous polymerase chain reaction 3D spiral microreactor capable of facile and on-demand fabrication

Qiushuang Yang, Wenchao Zhou, Huan Li, Jialing Huang, Zeyuan Song, Long Cheng, Yihui Wu and Deqiang Mu

Analytica Chimica Acta, 2024, 1310, 342692
DOI: 10.1016/j.aca.2024.342692

A novel method of droplet generation based on the self-propelling of water phase and its potential application in multiplexing continuous flow PCR

Xiaoguang Lu, Qianyue Jia, Yaning Zheng, Zishan Qin, Yong Li, Chao Shi and Cuiping Ma

Biosensors and Bioelectronics, 2025, 279, 117400
DOI: 10.1016/j.bios.2025.117400

Recent advancements in microfluidic-based biosensors for detection of genes and proteins: Applications and techniques

Saeed Siavashy, M. Soltani, Shayan Rahimi, Mehraveh Hosseinali, Zahra Guilandokht and Kaamran Raahemifar

Biosensors and Bioelectronics: X, 2024, 19, 100489
DOI: 10.1016/j.biosx.2024.100489

Lower fluidic resistance of double-layer droplet continuous flow PCR microfluidic chip for rapid detection of bacteria

Zhenqing Li, Yifei Wang, Zehang Gao, Shinichi Sekine, Qingxiang You, Songlin Zhuang, Dawei Zhang, Shilun Feng and Yoshinori Yamaguchi

Analytica Chimica Acta, 2023, 1251, 340995
DOI: 10.1016/j.aca.2023.340995

A Systematic Review of In Vitro Studies Using Microchip Platforms for Identifying Periodontopathogens from the Red Complex

Carlos M. Ardila, Gustavo A. Jiménez-Arbeláez and Annie Marcela Vivares-Builes

Dentistry Journal, 2023, 11, 245
DOI: 10.3390/dj11110245

Detection of Periodontal Pathogens Based on an Integrated Continuous Flow PCR and Capillary Electrophoresis Microfluidic Chip

Bo Yang, Jiaxin Huang, Chunxian Tao, Zhenqing Li, Dawei Zhang and Yoshinori Yamaguchi

Separations, 2023, 10, 271
DOI: 10.3390/separations10040271

Advances in Simple, Rapid, and Contamination-Free Instantaneous Nucleic Acid Devices for Pathogen Detection

Yue Wang, Chengming Wang, Zepeng Zhou, Jiajia Si, Song Li, Yezhan Zeng, Yan Deng and Zhu Chen

Biosensors, 2023, 13, 732
DOI: 10.3390/bios13070732

Customizable Nichrome Wire Heaters for Molecular Diagnostic Applications

Juhee Lim, Won Han, Le Tran Huy Thang, Yong Wook Lee and Joong Ho Shin

Biosensors, 2024, 14, 152
DOI: 10.3390/bios14030152