From the journal:

Chemical Communications

An AIE-active platinum complex for enhanced photodynamic therapy

Ping Liang,†a   Wenjing Li,†a   Ben Zhong Tang ORCID logo b  and  Guangxue Feng ORCID logo *a  

* Corresponding authors

a Deep-sited Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, State Key Laboratory of Luminescent Materials and Devices, School of Materials Science and Engineering, South China University of Technology, Guangzhou, China
E-mail: fenggx@scut.edu.cn

b Guangdong Basic Research Center of Excellence for Aggregate Science, School of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong 518172, China

Abstract

Conventional photodynamic therapy (PDT) suffers from aggregation-caused quenching and high oxygen dependence. Herein, we report a platinum (Pt)-coordinated photosensitizer (TPAQPt) for hypoxia-tolerant PDT. Inheriting aggregation-induced emission (AIE) features, high spin orbital coupling and intramolecular charge transfer ability, TPAQPt exhibits robust type I reactive oxygen species generation and a promising antitumor PDT effect.

Graphical abstract: An AIE-active platinum complex for enhanced photodynamic therapy

About
Cited by
Related
Download options Please wait...

Supplementary files

Transparent peer review

To support increased transparency, we offer authors the option to publish the peer review history alongside their article.

View this article’s peer review history

Article information

DOI
https://doi.org/10.1039/D5CC05324B
Article type
Communication
Submitted
16 Sep 2025
Accepted
11 Dec 2025
First published
12 Dec 2025

Chem. Commun., 2026, Advance Article

Permissions

Request permissions

An AIE-active platinum complex for enhanced photodynamic therapy

P. Liang, W. Li, B. Z. Tang and G. Feng, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D5CC05324B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements