MRI detection and grading of Knee Osteoarthritis - A pilot study using an AI technique with a novel imaging-based scoring system

Abstract

Precise and rapid identification of osteoarthritis (OA) is essential for efficient management and therapy planning. Conventional diagnostic techniques frequently depend on subjective interpretation, which have shortcomings, particularly during the first phases of the illness. In this study, magnetic resonance imaging (MRI) was used to create knee datasets as novel techniques for evaluating OA. This methodology utilizes artificial intelligence (AI) algorithms to identify and evaluate important indications of osteoarthritis, including osteophytes, eburnation, bone marrow lesions (BMLs), and Cartilage thickness. We conducted training and evaluation on multiple deep learning models, including ResNet50, DenseNet121, and VGG16, utilizing annotated MRI data. By conducting thorough statistical analysis and validation, we have proven the efficacy of our models in precisely diagnosing and grading OA. This research presents a new grading method, verified by experienced radiologists, that uses eburnation as a significant indicator of the severity of OA. This study provides a new method for AI-powered automated system designed to diagnose OA. This system will simplify the diagnostic process, minimize mistakes made by humans, and enhance the effectiveness of clinical treatment. Through the integration of AI-ML (machine learning) technologies, our goal is to improve patient outcomes, optimize the utilization of healthcare resources, and enable personalized OA therapy.

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Article information

Article type
Paper
Submitted
27 Mar 2025
Accepted
14 Aug 2025
First published
19 Aug 2025

Biomater. Sci., 2025, Accepted Manuscript

MRI detection and grading of Knee Osteoarthritis - A pilot study using an AI technique with a novel imaging-based scoring system

C. Roy, M. Roshan, N. Goyal, P. Rana, N. P. Ghonge, A. Jena, R. Vaishya and S. Ghosh, Biomater. Sci., 2025, Accepted Manuscript , DOI: 10.1039/D5BM00470E

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