Issue 28, 2016

Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein

Abstract

We report the crystal structure of a novel 60-subunit dodecahedral cage that results from self-assembly of a re-engineered version of a natural protein (PduA) from the Pdu microcompartment shell. Biophysical data illustrate the dependence of assembly on solution conditions, opening up new applications in microcompartment studies and nanotechnology.

Graphical abstract: Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein

  • This article is part of the themed collection: Foldamers

Supplementary files

Article information

Article type
Communication
Submitted
27 Jan 2016
Accepted
09 Mac 2016
First published
09 Mac 2016

Chem. Commun., 2016,52, 5041-5044

Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein

J. Jorda, D. J. Leibly, M. C. Thompson and T. O. Yeates, Chem. Commun., 2016, 52, 5041 DOI: 10.1039/C6CC00851H

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