Issue 4, 2024

A highly sensitive fluorescence probe for on-site detection of nerve agent mimic diethylchlorophosphonate DCP

Abstract

Nerve agents are the most toxic chemical warfare agents that pose severe threat to human health and public security. In this work, we developed a novel fluorescent probe NZNN based on naphthylimide and o-phenylenediamine to detect nerve agent mimic diethylchlorophosphonate (DCP). DCP underwent a specific nucleophilic reaction with the o-phenylenediamine group of NZNN to produce a significant fluorescence turn-on response with high selectivity, exceptional linearity, bright fluorescence, rapid response (<6 s) and a low detection limit (30.1 nM). Furthermore, a portable sensing device was fabricated for real-time detection of DCP vapor with excellent performance. This portable and sensitive device is favorable for monitoring environmental pollution and defense against chemical warfare agents.

Graphical abstract: A highly sensitive fluorescence probe for on-site detection of nerve agent mimic diethylchlorophosphonate DCP

Supplementary files

Article information

Article type
Paper
Submitted
23 Nov 2023
Accepted
21 Des 2023
First published
21 Des 2023

Anal. Methods, 2024,16, 515-523

A highly sensitive fluorescence probe for on-site detection of nerve agent mimic diethylchlorophosphonate DCP

C. Chen, W. Zhang, Y. Ke, L. Jiang and X. Hu, Anal. Methods, 2024, 16, 515 DOI: 10.1039/D3AY02091F

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