Issue 29, 2021

Chalcogen bonding mediates the formation of supramolecular helices of azapeptides in crystals

Abstract

To explore whether chalcogen bonding was able to drive the formation of supramolecular helices, alanine-based azapeptides containing a β-turn structure, with a thiophene group, respectively, incorporated in the N- or C-terminus, were employed as helical building blocks. While the former derivative formed a supramolecular M-helix via intermolecular S⋯S chalcogen bonding in crystals, the latter formed P-helix via intermolecular S⋯O chalcogen bonding.

Graphical abstract: Chalcogen bonding mediates the formation of supramolecular helices of azapeptides in crystals

Supplementary files

Article information

Article type
Communication
Submitted
31 Mei 2021
Accepted
05 Jul 2021
First published
05 Jul 2021

Org. Biomol. Chem., 2021,19, 6397-6401

Chalcogen bonding mediates the formation of supramolecular helices of azapeptides in crystals

D. Shi, J. Cao, P. Weng, X. Yan, Z. Li and Y. Jiang, Org. Biomol. Chem., 2021, 19, 6397 DOI: 10.1039/D1OB01053K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements