Issue 24, 2021

Optically superior fluorescent probes for selective imaging of cells, tumors, and reactive chemical species

Abstract

Fluorescent chemical probes have become powerful tools to study biological events in living cells. They provide a great opportunity to quantitatively and qualitatively analyze the physiological and biochemical properties of living cells in real time. The ability of researchers to manipulate these probes for a desired specific purpose has turned many heads in the scientific community. Despite a slow start, fluorescent probe research has seen exponential growth over the last decade in the world. This change required some adventurous and creative scientists from different fields—like biology, medicine, and chemistry—to come together to facilitate the constant expansion of this field. This review article introduces some fundamental concepts related to fluorescent probe designing and development. It also summarizes various fluorescent probes with superior optical properties used in fields like cell biology, cellular imaging, medical research, and cancer diagnosis. It is hoped that this article will encourage more young and creative scientists to contribute their talents to this field.

Graphical abstract: Optically superior fluorescent probes for selective imaging of cells, tumors, and reactive chemical species

Article information

Article type
Review Article
Submitted
16 Mac 2021
Accepted
22 Apr 2021
First published
22 Apr 2021

Org. Biomol. Chem., 2021,19, 5208-5236

Optically superior fluorescent probes for selective imaging of cells, tumors, and reactive chemical species

A. Saini, J. Singh and S. Kumar, Org. Biomol. Chem., 2021, 19, 5208 DOI: 10.1039/D1OB00509J

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