Issue 41, 2021
From the journal:

Chemical Communications

A tumor-targeted near-infrared fluorescent probe for HNO and its application to the real-time monitoring of HNO release in vivo†

Ziyin Chai,ab   Diankai Liu,a   Xiaoyi Li,a   Yanyan Zhao,a   Wen Shi, ORCID logo *ab   Xiaohua Li ORCID logo a  and  Huimin Ma ORCID logo *ab  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
E-mail: shiwen@iccas.ac.cn, mahm@iccas.ac.cn

b University of Chinese Academy of Sciences, Beijing 100049, China

Abstract

Nitroxyl (HNO) is a promising regulator for cancer therapy. Here, we develop a tumor-targeted near-infrared fluorescent probe for HNO and utilize it in the real-time imaging of HNO release in vivo.

Graphical abstract: A tumor-targeted near-infrared fluorescent probe for HNO and its application to the real-time monitoring of HNO release in vivo

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Article information

DOI
https://doi.org/10.1039/D1CC01462E
Article type
Communication
Submitted
18 Mac 2021
Accepted
09 Apr 2021
First published
22 Apr 2021

Chem. Commun., 2021,57, 5063-5066

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A tumor-targeted near-infrared fluorescent probe for HNO and its application to the real-time monitoring of HNO release in vivo

Z. Chai, D. Liu, X. Li, Y. Zhao, W. Shi, X. Li and H. Ma, Chem. Commun., 2021, 57, 5063 DOI: 10.1039/D1CC01462E

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