Issue 20, 2019

Synthesis of carbohydrate building blocks via regioselective uniform protection/deprotection strategies

Abstract

Discussed herein is the synthesis of partially protected carbohydrates by manipulating only one type of a protecting group for a given substrate. The first focus of this review is the uniform protection of an unprotected starting material in a way that only one (or two) hydroxyl group remains unprotected. The second focus involves regioselective partial deprotection of uniformly protected compounds in a way that only one (or two) hydroxyl group becomes liberated.

Graphical abstract: Synthesis of carbohydrate building blocks via regioselective uniform protection/deprotection strategies

Article information

Article type
Review Article
Submitted
11 Mac 2019
Accepted
24 Apr 2019
First published
02 Mei 2019

Org. Biomol. Chem., 2019,17, 4934-4950

Author version available

Synthesis of carbohydrate building blocks via regioselective uniform protection/deprotection strategies

T. Wang and A. V. Demchenko, Org. Biomol. Chem., 2019, 17, 4934 DOI: 10.1039/C9OB00573K

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