Liping Zhu, Jing Ye, Shuang Wang, Mengxia Yan, Qiuju Zhu, Jianshe Huang and Xiurong Yang
Chem. Commun., 2019,55, 11551-11554
DOI:
10.1039/C9CC05592D,
Communication
A novel ratiometric electrochemiluminescence (ECL)–electrochemical (EC) hybrid biosensor with a high accuracy and reproducibility was fabricated for the ultrasensitive detection of miRNA-133a. With the help of a DNA tetrahedron nanostructure and hybridization chain reaction dual amplification strategy, the detection limit of 12.17 aM for miRNA-133a was obtained.
